Ifren-S Soft Capsule (Dexibuprofen)

Adult dosage

Administer 300 mg of dexibuprofen orally, 2 to 4 times a day. Do not exceed 1,200 mg of dexibuprofen in a day.

Those who regularly consume 3 or more alcoholic drinks per day must consult with a doctor or pharmacist before taking this medication. This is because taking this medicine may increase the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular diseases. Special caution should be taken by individuals with a history of cardiovascular disease or risk factors, due to the possibility of serious thrombotic reactions such as myocardial infarction or stroke. This medication may cause serious abdominal issues such as gastrointestinal bleeding, ulcers, and perforations, particularly at greater risk in the elderly. Therefore, if gastrointestinal symptoms occur, consult a doctor immediately. Those with a history of gastric ulcers, bleeding, severe liver or kidney impairment, heart failure, hypertension, or allergies to aspirin or other non-steroidal anti-inflammatory drugs should not take this medication. Concurrent use with aspirin, other non-steroidal anti-inflammatory drugs, and high-dose methotrexate may increase the risk of side effects, so it is advisable not to combine them. Breastfeeding should be avoided while taking this medication, and care should be taken when driving or operating machinery as dizziness or fatigue may occur. Individuals with blood abnormalities, liver or kidney diseases, hypertension, heart failure, or a history of allergies should consult a doctor or pharmacist before taking this medication. If serious symptoms such as shock, severe skin rash, difficulty breathing, blood abnormalities, liver function abnormalities, or kidney issues occur while taking this medication, discontinue use immediately and consult medical staff. This medication should be used at the minimum effective dose and for the shortest duration possible, and regular blood tests as well as liver and kidney function tests are important. During pregnancy, especially after 6 months, it may be harmful to the fetus, so its use should be avoided, and women who plan to become pregnant or may be pregnant should also consult before use. In case of overdose, even without symptoms, immediate treatment at a medical facility is required, and the medication should be kept out of reach of children, protected from direct sunlight, and stored in a cool, dry place.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, shock, anaphylactic shock, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, erythema multiforme, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), drug rash, hematological abnormalities (aplastic anemia, hemolytic anemia, agranulocytosis, leukopenia, agranulosis, pancytopenia)

Mild side effects

• Dyspepsia
• abdominal bloating
• heartburn
• upper abdominal pain
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

Do not take this medication with aspirin, other non-steroidal anti-inflammatory drugs, and high-dose methotrexate (15 mg/week or more) used in cancer therapy. Corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors, angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants (warfarin, etc.), baclofen, and immunosuppressants (cyclosporine) may interact as well.

This medication should be stored in a tightly sealed container to protect it from air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. This way, the effectiveness of the medication can be well maintained.

Appearance

Light green transparent soft capsule containing a colorless to pale turquoise transparent liquid

Package unit

10 capsules (10 capsules/PTP*1)