Medication info

Propainfusion Injection (Acetaminophen)

Prescription medication
Ingredient · strength
Acetaminophen›10mg / 1mL
Manufacturer / importer
대한약품공업(주)
Appearance
Clear, light yellow injection solution in a colorless vial or polypropylene container
Packaging
Bottle - 50 milliliters/bottle, Bottle - 75 milliliters/bottle, Bottle - 100 milliliters/bottle, Bag - 100 milliliters/bag
Approval status
Active

MFDS item code 200902008 · Approved 2009.03.18

Summary

Main use
Rapid short-term treatment of moderate pain (post-surgery) and fever
Who uses it
Adults · Children
Adult dosage
For adults weighing 50 kg or more: Administer acetaminophen 1000 mg four times a day. Dosing interval: at least 4 hours. Maximum daily dose: must not exceed 4 grams. For children weighing 33 kg or more and adults weighing less than 50 kg: Administer approximately 15 mg/kg of acetaminophen (1.5 ml/kg of this medication) for a single dose. Dosing interval: at least 4 hours. Maximum daily dose: must not exceed 60 mg/kg or 4 grams.
Children's dosage
For children weighing 33 kg (approximately 11 years) or more: Administer approximately 15 mg/kg of acetaminophen (1.5 ml/kg of this medication) for a single dose. Dosing interval: at least 4 hours. Maximum daily dose: 60 mg/kg or

Ingredients

Manufacturer
대한약품공업(주)

Efficacy & effects

Rapid short-term treatment of moderate pain (post-surgery) and fever

  • Moderate pain
  • post-surgical pain
  • fever
View approved original text

This medication is used when it must be administered intravenously due to pain or high fever, or when other routes of administration are difficult. It effectively alleviates moderate pain that occurs after surgery in a short period of time. It also helps to treat fever over a short term. It acts quickly and safely to alleviate the discomfort of patients experiencing these symptoms. Therefore, this medication is suitable for the treatment of post-surgical pain and acute fever.

Dosage and Administration

Adult dosage

For adults weighing 50 kg or more: Administer acetaminophen 1000 mg four times a day. Dosing interval: at least 4 hours. Maximum daily dose: must not exceed 4 grams. For children weighing 33 kg or more and adults weighing less than 50 kg: Administer approximately 15 mg/kg of acetaminophen (1.5 ml/kg of this medication) for a single dose. Dosing interval: at least 4 hours. Maximum daily dose: must not exceed 60 mg/kg or 4 grams.

Children's dosage

For children weighing 33 kg (approximately 11 years) or more: Administer approximately 15 mg/kg of acetaminophen (1.5 ml/kg of this medication) for a single dose. Dosing interval: at least 4 hours. Maximum daily dose: 60 mg/kg or

Precautions

This medication must be used with great caution to avoid overdose due to confusion between milligrams and milliliters when administered. Once oral administration becomes possible, it is recommended to use an appropriate analgesic immediately. Be sure to check if other medications contain acetaminophen to prevent overdose. Exceeding the recommended doses can lead to serious liver damage, so dosage must be strictly followed. Patients with impaired liver function or those who consume alcohol frequently should consult a doctor before taking this medication. This medication may rarely cause severe allergic reactions on the skin, and if a rash or hypersensitivity occurs, it must be discontinued immediately. Patients allergic to acetaminophen or this medication, those with severe liver dysfunction, kidney dysfunction, or heart failure should not use it. Certain patients, such as those with liver dysfunction, kidney dysfunction, peptic ulcers, blood disorders, elderly patients, pregnant women, and nursing mothers, must use this medication carefully and it's important to consult a doctor. This medication does not affect driving or operating machinery, and it should not be mixed with other medications. Symptoms of infection may be masked during use, so infected patients should use it alongside appropriate antibiotics as directed by a doctor. During pregnancy, the benefits and risks of this medication should be carefully evaluated prior to use, and it can be safely used while breastfeeding. In case of overdose, symptoms such as nausea, vomiting, loss of appetite, and abdominal pain may appear, and in severe cases, it can lead to liver failure and coma, necessitating immediate medical attention. This medication should be stored at room temperature below 30 degrees Celsius, avoiding refrigeration or freezing, and before administration, the solution must be checked for any foreign substances or discoloration. Unused solutions should be discarded, and it should be used only once.

Side effects and when to seek care immediately

Serious side effects

Hives, anaphylactic shock, acute generalized exanthematous pustulosis, toxic epidermal necrolysis, Stevens-Johnson syndrome, shock, agranulocytosis, neutropenia, leukopenia, thrombocytopenia, coma, acute kidney failure, Lyell's syndrome, thrombocytopenic purpura, fulminant hepatitis, hepatic necrosis, liver failure, increased liver enzymes, angioedema, anaphylaxis, severe allergic reactions, severe skin adverse reactions, severe edema, and others.

Mild side effects

  • Lethargy
  • hypotension
  • increased levels of liver transaminases
  • neurological disorders
  • rashes
  • injection site reactions
  • nausea
  • vomiting
  • headache
  • constipation
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  • phlegm
  • sensory abnormalities
  • dizziness
  • decreased hemoglobin
  • urinary disorders
  • tachycardia
  • nausea
  • erythema
  • flushing
  • itching
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored at room temperature between 1 and 30 degrees Celsius, and it is important to keep it sealed in a container to prevent air or moisture from entering. Storing it this way will help maintain its effectiveness for a long time.

Appearance and packaging

Appearance

Clear, light yellow injection solution in a colorless vial or polypropylene container

Package unit

Bottle - 50 milliliters/bottle, Bottle - 75 milliliters/bottle, Bottle - 100 milliliters/bottle, Bag - 100 milliliters/bag

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.