Combiplex M City Peri Injection

Adult administration

Administer via peripheral vein. The infusion rate should be determined considering the total volume to be infused, the characteristics of the final mixed solution, daily dose, and infusion time. Typically, the infusion rate should be gradually increased over the first 30 minutes to 1 hour to reach the appropriate volume. Infusion over 12 to 24 hours is preferable. Do not administer for more than 7 days. The maximum infusion rate should not exceed 2.5 mL/kg/hour.

This medication should only be used according to a physician's instructions. If severe allergic reactions such as anaphylaxis occur, administration should be stopped immediately. When used with the drug Ceftriaxone, precipitates may form, so the same infusion device should not be used simultaneously. Particular caution is advised when administering to premature or low-birth-weight infants, as lipid metabolism may be problematic. Patients with a history of prematurity, neonates, egg or soybean oil allergies, severe renal failure, or liver disease should not use this medication. Patients with specific diseases such as renal failure, diabetes, or liver dysfunction must use this medication cautiously and have their blood lipid levels frequently monitored. Excessive dosing or rapid infusion can lead to adverse effects, so caution is required. If symptoms such as fever, chills, headaches, vomiting, or difficulty breathing occur during administration, stop the administration immediately. Regular liver function and blood tests should be performed in patients using the medication for an extended period. Caution must be exercised when administering this medication concurrently with blood, as blood coagulation may occur. Pregnant or breastfeeding women should consult with a physician to determine whether to use this medication. If blood tests are to be conducted within a few hours after administration, the drug components may affect the test results, so it is recommended to have the tests done at an appropriate time. In cases of overdose, symptoms such as acidosis, hypervolemia, hyperglycemia, dehydration, or pulmonary edema may arise, necessitating immediate notification to medical personnel and appropriate treatment. Do not use the medication if it is damaged or deteriorated, and use it quickly after opening, disposing of any remaining medication afterwards. Store in a sealed container away from air or light. It is best to keep it in a cool place between 15 and 25 degrees Celsius, and do not freeze.

Serious side effects

• Fever
• rash
• difficulty breathing
• hepatomegaly
• jaundice
• coma
• increased blood pressure
• coagulation abnormalities
• pulmonary edema
• liver dysfunction

Mild side effects

Increased body temperature, sweating, chills, headache, vomiting, loss of appetite, nausea, pain in the back, bones, chest, or waist, increased or decreased blood pressure, skin rash, cyanosis, hepatomegaly, splenomegaly, adipose accumulation in tissues, anemia, decreased white blood cell count, decreased platelet count, altered coagulation components or reduction, abnormal blood symptoms, fever, hyperlipidemia, abdominal pain, fatigue, venous irritation symptoms (thrombophlebitis, thrombotic venous inflammation), vomiting,

This medication should be stored in a sealed container to avoid exposure to air or light. It is advisable to keep it in a cool place between 15 and 25 degrees Celsius.

Appearance

This drug consists of an internal bag and external packaging made of polypropylene, divided into three compartments, with an oxygen absorber in between. Each internal bag compartment contains dextrose and

Package unit

250 mL/bag, 375 mL/bag, 1250 mL/bag, 1875 mL/bag