Losartan-Hydrochlorothiazide Plus Tablet

Adult dose

The standard dosage for this medication is one tablet of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once a day. Doses exceeding losartan potassium 100 mg/hydrochlorothiazide 25 mg per day are not advisable. For patients whose blood pressure is not controlled with losartan or hydrochlorothiazide monotherapy, treatment should be initiated with one tablet of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once a day.

Child dose

There is no experience with the use in children and adolescents, therefore the losartan-hydrochlorothiazide combination should not be administered to children and adolescents.

This medication can cause serious harm to the fetus when used during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with a known allergy to this medication or its components, severely impaired kidney function, severe liver dysfunction, pregnant women, or women of childbearing potential should not use this medication. Patients with hypotension, kidney issues, liver dysfunction, hyperuricemia, electrolyte imbalance, or cerebrovascular diseases should use this medication with special care. This medication lowers blood pressure and may cause side effects such as dizziness, headache, cough, and edema in some patients. The hydrochlorothiazide component may cause electrolyte imbalances, so regular blood tests are recommended, and any signs of dehydration or electrolyte abnormalities should be reported to a doctor immediately. During treatment, potassium supplements or potassium-containing salt substitutes should not be taken without consulting a doctor. Additionally, this medication may increase skin sensitivity to sunlight, so prolonged sun exposure should be avoided, and any skin abnormalities should be reported immediately. Dizziness or drowsiness may occur while driving or operating machinery, so caution is advised. There may be interactions with other medications, so inform your doctor or pharmacist of any other medications you are currently taking. The safety and efficacy in children and adolescents have not been established, so it is not used in this population. Elderly patients may experience side effects more frequently, so they should take this medication according to medical advice. Store this medication in its original container, out of reach of children, and do not change or store it in a different container.

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, jaundice (yellowing of skin or eyes), severe fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, markedly reduced urine output, severe systemic swelling with associated increase in blood pressure

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication should be stored in a tightly closed container that can block light and at a temperature between 1 to 30 degrees Celsius. This storage method helps maintain the medication's efficacy for a long time.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle