Zocor 40mg (Simvastatin)

Adult dose

1. Reduction of risk for cardiovascular disease: the initial dosage is 40 mg of simvastatin once daily. 2. Hyperlipidemia: - The typical initial dosage is 20 mg administered once daily in the evening. - Patients with mild to moderate hypercholesterolemia may start with 10 mg. - The recommended dosing range is 5-40 mg once daily in the evening. - Before starting treatment, establish the initial LDL cholesterol level, treatment goals, and patient's response to medication.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17): initial dose of 10 mg once daily in the evening. The recommended dosage range is 10-40 mg once daily, with a maximum recommended dose of 40 mg.

This medication may cause muscle-related side effects such as myopathy and rhabdomyolysis, so caution is necessary, especially when taking high doses. Patients with liver dysfunction or active liver disease should not take this medication. It is safest for pregnant women or those who may become pregnant, as well as nursing mothers, to avoid this medication. The risk of muscle side effects increases when taken with certain strong medications, so consultation with a physician is required when taking such medications. Patients with a history of alcohol abuse or liver and kidney dysfunction should exercise additional caution while taking this medication and report immediately to healthcare providers if they experience muscle pain or weakness. Elderly individuals and women are at higher risk for muscle-related side effects and should be cautious while taking this medication. Regular monitoring of liver function and muscle status during the use of this medication is advisable. Any potential interactions with other medications, health supplements, or grapefruit juice should be discussed with healthcare providers prior to use. If unexplained muscle pain, tenderness, or weakness occurs during the use of this medication, inform a doctor immediately and potentially stop taking the medication. Additionally, this medication may increase blood sugar levels, so patients at risk for diabetes should regularly monitor their blood glucose levels. This medication is not recommended for children, especially those under 10 years of age, and adolescents over 10 years should take it under medical guidance. This medication should be stored out of reach of children, and it is advisable to keep it in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/eye mucosal pain, difficulty inhaling or breathing, asthma attacks, cough with fever accompanied respiratory abnormalities, skin or eyes turning yellow (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination

Mild side effects

Muscle pain, muscle cramps, joint pain, abdominal pain, weakness, constipation, diarrhea, dyspepsia, bloating, nausea, headache, upper respiratory tract infection, atrial fibrillation, gastritis, insomnia, dizziness, bronchitis, chills, eczema, urinary tract infection, alopecia, itching, various skin changes, flat drug rashes, gynecomastia, decreased libido, sexual dysfunction, cataract progression, anemia, thyroid dysfunction, transient and mild liver function test abnormalities, diabetes

This medication should be stored in a tightly sealed container to prevent air or humidity ingress and kept away from direct sunlight at a cool room temperature below 30 degrees Celsius. Storing it this way helps maintain the efficacy of the medication for a longer period.

Appearance

Oval film-coated tablet, red brick color with MSD749 engraved on one side

Package unit

30 tablets/box [(10 tablets/PTP x 3)]