Diquban Tablet 160 mg (Valsartan)

Adult dose

For essential hypertension, take with water during meals or in-between meals. It is recommended to take it at the same time every day (e.g., morning). As valsartan, the recommended dose is 80 mg orally once a day. Patients whose blood pressure is not well controlled may increase the dosage to 160 mg once daily or combine with a diuretic. If further blood pressure reduction is needed, the dosage can be increased up to a maximum of 320 mg once daily. Elderly patients (75 years or older): start with a dose of 40 mg once daily. Patients with renal impairment: (1) Creatinine clearance 20 to 50 mL/min: No dose adjustment necessary. (2) Creatinine clearance 10 to 20 mL/min: Start with a dose of 40 mg once daily. (3) Creatinine clearance below 10 mL/min and dialysis patients: this medication should not be administered. (4) Patients with reduced body fluid: Patients with low blood volume (e.g., those on high doses of diuretics who cannot reduce the dose) should start with a dose of 40 mg once daily. (5) Patients with liver impairment: Mild to moderate liver impairment should start with a dose of 40 mg once daily and not exceed 80 mg. In severe liver impairment, liver cirrhosis, or cholestasis, this medication should not be used. (6) Children: Safety and efficacy have not been established in children and adolescents under 18 years of age.

Child dose

Safety and efficacy have not been established in children and adolescents under 18 years of age.

This drug can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. Patients with known allergies to this medication or its ingredients, women who are pregnant or breastfeeding, patients with severe liver or kidney disease, and those with a history of angioedema should not take this medication. Elderly patients, those with high potassium levels, liver disease, and cardiovascular disease should use this medication with caution, as they may experience hypotension or changes in kidney function, so their conditions should be monitored closely. During treatment with this medication, side effects such as dizziness, headache, fatigue, cough, and diarrhea may occur, and rarely severe allergic reactions or kidney dysfunction may develop, so consult a doctor immediately if symptoms arise. Blood pressure may drop suddenly or fainting may occur, so especially when starting treatment, it is important to begin with a low dose and monitor the condition closely. When taken together with other antihypertensive drugs, diuretics, or potassium-sparing medications, interactions may cause dangerously high potassium levels, so patients must inform their doctor of all medications they are taking. Women who are pregnant or planning a pregnancy should not take this medication, and its use is not recommended during breastfeeding. Use is not recommended for children or adolescents under 18 years of age, as safety and efficacy have not been established. In the case of overdose, blood pressure may drop too low, so seek appropriate medical treatment immediately.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eye, shortness of breath or difficulty breathing, asthma attack, respiratory problems accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues.

Mild side effects

• Headache
• dizziness
• viral infection
• upper respiratory tract infection
• cough
• diarrhea
• fatigue
• rhinitis
• sinusitis
• back pain

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is also important to store it in a cool place below 30 degrees to maintain its efficacy.

Appearance

Oval film-coated tablet, orange with a grayish tint

Package unit

30 tablets/bottle