Allervan Liquid (Levocetirizine Hydrochloride)

Adult dose

For adults and children over 6 years of age, the dosage is 5mg (10mL as liquid) administered orally once a day, regardless of meal timing. In adults with renal impairment, the dose should be adjusted according to renal function (estimated glomerular filtration rate (eGFR)). eGFR ≥ 90 (normal kidney function): 5mg once a day 60 - < 90 (mild kidney impairment): 5mg once a day 30 - < 60 (moderate

Child dose

For children over 2 years and less than 6 years old, the dose is 1.25mg (2.5mL as liquid) administered orally twice a day. For children over 1 year and less than 2 years old, the dose is 1.25mg (2.5mL as liquid) administered orally once a day.

This medication should not be used by patients with a history of allergy or hypersensitivity to certain ingredients. Patients with end-stage kidney disease or undergoing dialysis should not take this medication. It should not be administered to infants under 1 year of age, and children under 6 should take it in liquid form, not tablets. The liquid formulation contains maltitol, so patients with a congenital inability to digest fructose should avoid taking it. Caution is advised when administering to patients with reduced kidney or liver function, as drug concentrations may increase, especially in the elderly. Taking this medication may lead to various neurological side effects such as drowsiness, headache, dizziness, and fatigue. Gastrointestinal symptoms may include dry mouth, nausea, abdominal pain, and diarrhea. Rarely, cardiac side effects such as increased heart rate or arrhythmias have been reported. Blood-related issues may include leukopenia or changes in platelet count. Allergic reactions may occur, such as skin rash, itching, swelling, and in severe cases, anaphylactic shock. Visual disturbances or conjunctival hyperemia may occur. Liver function tests may temporarily rise, so caution regarding liver health is advised. Kidney function may also be affected, leading to changes in blood test results. Common side effects in children may include fever, diarrhea, vomiting, and otitis media. Drowsiness or fatigue may occur after taking this medication, so caution is needed when driving or operating machinery. Taking this medication in conjunction with alcohol or central nervous system depressants may increase drowsiness, so it should be avoided. Patients with urinary retention should be cautious as symptoms may worsen when taking this medication. Patients with epilepsy or those at risk of seizures should consider the potential for exacerbation of their condition while taking this medication. The liquid form contains preservatives and sweeteners, which may cause allergic reactions or be harmful to health. Taking this medication with alcohol may increase the central nervous system depressant effect, so they should not be taken together. Due to limited data on the safety of this medication during pregnancy, caution is advised. Women who are breastfeeding should be careful as this medication may be excreted in breast milk and could affect the baby. It should not be used in infants under 1 year, and dosage adjustment is required for children under 12 years old. Elderly patients may have increased drug concentrations due to renal impairment and should start at a lower dosage with careful monitoring. It is advisable to discontinue this medication before allergy testing, and in the case of overdose, immediate consultation with healthcare providers for appropriate treatment is necessary. There is no antidote for overdose, and symptomatic treatment is necessary, as the drug is not effectively removed by hemodialysis.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, numbness, urinary retention

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• anxiety
• malaise
• fatigue
• dizziness
• heaviness in the head
• excitement

This medication is sensitive to light, so it should be stored in a container that blocks light. Additionally, it is best stored at room temperature between 1°C and 30°C. Storing it this way helps maintain the medication's effectiveness.

Appearance

Colorless and transparent solution in a brown glass or plastic bottle

Package unit

100 milliliters per bottle