Letisin (Levocetirizine Hydrochloride)

Adult dose

Adults and children over 6 years: 5 mg (10 mL in liquid form) orally once a day, regardless of meals. Adults with renal impairment should adjust the dosage based on renal function (estimated glomerular filtration rate (eGFR)). - Normal renal function (≥ 90 mL/min): 5 mg once a day - Mild renal impairment (60 -< 90 mL/min): 5 mg once a day - Moderate

Child dose

Children aged 2 years and older but under 6 years: 1.25 mg (2.5 mL in liquid form) once, twice a day orally. Children aged 1 to under 2 years: 1.25 mg (2.5 mL in liquid form) once a day.

This medication should not be used by patients who have had an allergic reaction or hypersensitivity to any of the components. It should not be administered to patients with end-stage renal disease or those on dialysis. It should not be used in infants under 1 year old, and children under 6 years old should take it in liquid form, not pill form. The liquid form contains maltitol, so patients with hereditary fructose intolerance should avoid this medication. Patients with diminished renal or liver function, as well as the elderly, should use caution as the drug concentration in the blood may increase. Taking this medication may cause neurological symptoms such as drowsiness, headaches, dizziness, and fatigue; therefore, caution is advised when driving or operating machinery. Gastrointestinal discomfort such as nausea, abdominal pain, and diarrhea may occur; if symptoms are severe, it is recommended to consult a physician. Caution is advised for patients with heart disease, as there is a risk of increased or irregular heartbeats. Allergic reactions may cause skin rashes, itching, or swelling; any unusual symptoms should be reported to medical personnel immediately. This medication can cause drowsiness and fatigue, so it is recommended to avoid taking it with alcohol or other central nervous system depressants. Patients at risk for urinary obstruction should use this medication with caution, and those with epilepsy or a risk of seizures should use it carefully as their condition may worsen. Women who are pregnant or breastfeeding should take care regarding the effects of this medication on the fetus or newborn. Children and the elderly may experience different drug effects and side effects based on their body functions; thus, appropriate dosage adjustment and monitoring are necessary. This medication may affect the results of allergy tests, so it is advisable to discontinue use before testing. In case of overdose, symptoms such as drowsiness or anxiety may appear, and as there is no specific antidote, appropriate treatment should be provided according to the symptoms. This medication is not removed by dialysis, so rapid medical intervention is necessary in cases of overdose.

Serious side effects

• Urticaria
• severe swelling (edema)
• angioedema
• anaphylactic shock
• hypertension
• difficulty breathing
• urticaria

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• anxiety
• somnolence
• fatigue
• dizziness
• heaviness in the head
• excitement

Store this medication in a sealed container that can block light, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. This storage method will help maintain the medication's effectiveness for a longer period.

Appearance

Colorless and transparent solution in a brown glass or plastic bottle

Package unit

100 mL/bottle, 500 mL/bottle