Ravosol Injection

Adult dosage

Administer a maximum of 1 to 1.5 g of total amino acids per day per kg of body weight via drip infusion. A concentration of approximately 10 g of total amino acids is desired over a period of 60 minutes, with a guideline of administering 30 to 40 drops over 1 minute.

Children's dosage

In children, the dosage and infusion rate should be adjusted accordingly.

This drug must be used strictly according to a doctor's instructions, as taking it on your own judgment may be dangerous. It should not be used in patients with hepatic coma symptoms or a possibility of such, patients with severe kidney dysfunction, patients with problems in nitrogen metabolism, patients with severe heart failure, patients with pulmonary edema, patients with very little urine output, patients with abnormally high sodium or chloride levels, and patients with a history of myocardial infarction. Careful administration is required in patients with severe acidosis, congestive heart failure, edema due to sodium retention, hyperkalemia, and those with liver or kidney dysfunction. This drug contains sodium bisulfite, which may cause serious allergic reactions or asthma attacks in patients allergic to sulfites. Caution is required. Rarely, hypersensitivity reactions such as skin rashes may occur during use, and if such symptoms appear, administration should be stopped immediately. Occasionally, gastrointestinal symptoms such as nausea or vomiting, chest discomfort, palpitations, rapid heart rate, and elevated blood pressure may occur as cardiovascular side effects. Caution is needed as acidosis may occur if the drug is administered quickly and in large amounts. Symptoms such as chills, fever, headache, shortness of breath, shock, bronchospasm, and urinary tract spasms have also been reported. Metabolic acidosis, hypophosphatemia, alkalosis, hyperglycemia, diabetes, dehydration, rebound hypoglycemia, elevated liver enzyme levels, vitamin imbalances, electrolyte abnormalities, and in children, hyperammonemia may occur. Patients with impaired kidney function may experience elevated blood urea nitrogen levels, and patients with liver dysfunction may exhibit serum amino acid imbalances, metabolic alkalosis, hyperammonemia, and coma. Serious adverse reactions related to this drug include anaphylactic shock, so one must always be vigilant for adverse reactions. When administered in large quantities or with electrolytes, electrolyte balance should be closely monitored, as excessive administration may cause metabolic alkalosis. For patients with kidney disease, lung disease, or severe heart disease, dosage and rate should be adjusted to avoid fluid overload. Diabetic patients are advised to frequently monitor blood sugar levels while using this drug. The efficacy of this drug may be reduced when used in combination with certain antibiotics, so it's advisable to consult with a physician. Safety during pregnancy has not been established, so it should be used only when the therapeutic benefit outweighs the risks. In pediatric patients, since liver function may not be fully developed, hyperammonemia may occur, thus care should be taken to maintain a low administration concentration and frequently check blood ammonia levels. Elderly patients may have reduced physiological functions, so careful attention is needed to slow the administration rate and adjust dosages. This drug contains electrolytes and can cause chills or vomiting if infused rapidly, so it should be administered slowly via intravenous injection. The infusion solution should be prepared and managed in a sterile condition, and discolored or leaking solutions should not be used.

Serious side effects

• Anaphylactic shock
• shortness of breath
• respiratory arrest
• shock
• bronchospasm
• immune system adverse reactions.

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• rapid pulse (tachycardia)
• elevated blood pressure
• chills
• fever
• headache

This drug should be stored in a sealed container to avoid contact with air. It is important to maintain the storage temperature between 1 and 30 degrees Celsius. This helps to preserve the efficacy of the drug.

Appearance

This drug is a transparent solution that is colorless to slightly yellow in color, contained in a multilayer film plastic container or a polypropylene aqueous injection container.

Package unit

250mL/box