Ciprofloxacin Tablet

Adult dosage

○ The usual adult dose is 300～600 mg of ofloxacin per day, divided into 2～3 doses. ○ For leprosy, take 400～600 mg of this medicine per day, divided into 2～3 doses. In principle, use in combination with other antileprosy drugs. The dose may be adjusted appropriately according to age and symptoms.

This medication may cause tendon-related issues such as tendinitis and tendon rupture, as well as peripheral neuropathy and central nervous system symptoms. If serious adverse symptoms occur, you must immediately discontinue this medication. Patients with myasthenia gravis should avoid using this medication as it may worsen their symptoms. This medication is only used for specific bacterial infections and should only be administered when no other treatment options are available. Caution is required for the elderly, patients with reduced kidney function, organ transplant recipients, or those taking corticosteroids, as the risk of tendon rupture is increased. Avoid concurrent use with corticosteroids, and if tendonitis or tendon rupture symptoms occur, discontinue and rest immediately. This medication has a neuromuscular blocking effect that may worsen symptoms in patients with myasthenia gravis, so cautious use is advised. Patients with hypersensitivity, previous tendon issues related to this medication or similar drugs, those under 18 years, pregnant or nursing women, those with certain enzyme deficiencies, and those with a history of seizures should not take this medication. Patients severely impaired in kidney or liver function, the elderly, those with a history of mental disorders, or aortic disease history must use this medication with utmost caution. Rarely, serious side effects such as anaphylactic shock, severe skin reactions, hepatitis, renal failure, gastrointestinal bleeding, neuropsychiatric symptoms, muscle and joint pain, respiratory issues, and cardiac arrhythmias may occur. During the medication period, one should avoid excessive sun exposure, and if rashes or skin abnormalities appear, stop immediately. Special caution must be taken for patients with epilepsy or brain-related conditions due to the risk of seizures. If a seizure occurs, discontinue the medication. Regular liver, kidney, and blood tests should be conducted during long-term use. Adequate hydration is necessary to reduce kidney burden, and as dizziness or drowsiness may occur, driving or operating dangerous machinery should be avoided. Blood glucose variations may occur when taken with glucose-regulating medications, so blood sugar must be monitored carefully. Due to numerous drug interactions, especially with anticoagulants, antidiabetic agents, antacids, and immunosuppressants, consulting with a physician or pharmacist is essential when co-administering. Women who are pregnant or potentially pregnant, as well as nursing mothers, should not use this medication and must discontinue breastfeeding. Safety has not been established for children and adolescents in growth, so it should not be used. The elderly may experience increased blood concentration of this medication due to declining kidney function, so dosage and dosing intervals need adjustment. In case of overdose, symptoms such as dizziness, nausea, facial swelling may appear, and immediate medical attention should be sought along with adequate hydration. When administered as an injection, it should be infused slowly and not mixed with other drugs. Lastly, this medication must be stored out of reach of children, and it is safer not to transfer it to another container.

Tendonitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reactions, rash, itching, redness, swelling, fever, warmth, photosensitivity reactions, hematuria, acute renal failure, kidney stones, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, abdominal pain, diarrhea, nausea, vomiting, gastrointestinal discomfort, cirrhosis, loss of appetite, abdominal pain, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, bowel perforation, anemia, leukopenia, reduced hemoglobin, reduced hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechial and ecchymotic hemorrhage, prolonged prothrombin time, bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, nervous hyperactivity, sleep disorders, confusion, anxiety, depression, agitation, dysphoria, delusions, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal thoughts, suicide, perceptual disturbances, olfactory and vestibular disturbances, ataxia, aphasia, heaviness of the head, skin and mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, fatigue, elevated CPK, elevated myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, nosebleed, wheezing, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, pruritus of the female external genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, malaise, fever, drowsiness, nausea, dizziness, flushing of the face, facial swelling, numbness, inaccurate pronunciation, loss of directional sense

This medication should be stored in a tightly sealed container to prevent air from entering and should be kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer time.

Appearance

White to light yellow round film-coated tablet

Package unit

In-house packaging unit