Medication info
Weltra Tablets

Weltra Tablets

Prescription medicationTablet경구
Ingredient · strength
Tramadol Hydrochloride›37.5mg / 1 tabletAcetaminophen›325mg / 1 tablet
Manufacturer / importer
(주)에이프로젠바이오로직스
Appearance
Pale yellow oblong film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200805631 · Notified 2008.05.20 · Insurance code 645203440

Summary

Main use
Relief of moderate to severe acute and chronic pain
Who takes it
Adults · Children
Adult dose
Children aged 12 and over, and adults: Dosage is adjusted based on the severity of the patient's pain and treatment response. It is recommended to start with 2 tablets as the initial dose, and the interval between subsequent doses should be at least 6 hours, but the daily maximum should not exceed 8 tablets. The effective lowest dose should be given for the shortest duration possible. Avoid administering prolonged treatment with this medication beyond necessity, and if long-term administration is required due to the nature and severity of the disease, carry out regular monitoring to confirm the continuation of this medication. Elderly patients Administer the standard adult dosage. However, since the elimination half-life of tramadol increased by 17% when orally administered to elderly patients aged 75 and older, dosing intervals should be at least 6 hours apart. Patients with renal impairment For moderate renal failure patients (creatinine clearance of 10-30 ml/min), extend the administration interval to 12 hours. For severe renal failure patients (creatinine clearance of less than 10 ml/min), administration is not recommended. Tramadol is removed very slowly during blood dialysis, so there is no need to readminister this medication after dialysis to maintain analgesic effects. Patients with liver impairment For moderate liver failure patients, carefully consider extending the interval between doses. For severe liver failure patients, this medication should not be administered.
Child dose
Children aged 12 and over, and adults: Dosage is adjusted based on the severity of the patient's pain and treatment response. It is recommended to start with 2 tablets as the initial dose, and the interval between subsequent doses should be at least 6 hours, but not exceed 8 tablets per day.

Ingredients

Manufacturer
(주)에이프로젠바이오로직스

Efficacy & effects

Relief of moderate to severe acute and chronic pain

  • Moderate to severe acute pain
  • moderate to severe chronic pain
View approved original text

This medication is used to relieve acute and chronic pain that ranges from moderate to severe.

How to take

Adult dose

Children aged 12 and over, and adults: Dosage is adjusted based on the severity of the patient's pain and treatment response. It is recommended to start with 2 tablets as the initial dose, and the interval between subsequent doses should be at least 6 hours, but the daily maximum should not exceed 8 tablets. The effective lowest dose should be given for the shortest duration possible. Avoid administering prolonged treatment with this medication beyond necessity, and if long-term administration is required due to the nature and severity of the disease, carry out regular monitoring to confirm the continuation of this medication. Elderly patients Administer the standard adult dosage. However, since the elimination half-life of tramadol increased by 17% when orally administered to elderly patients aged 75 and older, dosing intervals should be at least 6 hours apart. Patients with renal impairment For moderate renal failure patients (creatinine clearance of 10-30 ml/min), extend the administration interval to 12 hours. For severe renal failure patients (creatinine clearance of less than 10 ml/min), administration is not recommended. Tramadol is removed very slowly during blood dialysis, so there is no need to readminister this medication after dialysis to maintain analgesic effects. Patients with liver impairment For moderate liver failure patients, carefully consider extending the interval between doses. For severe liver failure patients, this medication should not be administered.

Child dose

Children aged 12 and over, and adults: Dosage is adjusted based on the severity of the patient's pain and treatment response. It is recommended to start with 2 tablets as the initial dose, and the interval between subsequent doses should be at least 6 hours, but not exceed 8 tablets per day.

Precautions

This medication may put a burden on the liver, so individuals who regularly consume more than three glasses of alcohol daily must consult a doctor or pharmacist before taking this drug. While taking this medication, serious skin reactions such as rashes or blisters may occur; if such symptoms appear, immediately discontinue use and inform medical personnel. One of the active ingredients in this drug, tramadol, can induce seizures, so patients with a history of seizures or those at high risk of seizures should use this medication with caution, and the risk of seizures may increase when taken with certain antidepressants or narcotic analgesics. Rarely, severe allergic reactions may occur after taking this drug, so if symptoms such as difficulty breathing or hives develop, seek medical assistance immediately. This medication may impair breathing in acute asthma patients, so it should only be used in environments where medical equipment is prepared. Taking this drug in conjunction with alcohol or central nervous system depressants may lead to severe drowsiness, respiratory depression, or coma; thus, great caution is advised when combining these substances. Patients with head injuries or elevated intracranial pressure should use this medication cautiously, as it may worsen symptoms due to respiratory depression and increased brain pressure. This drug can lead to physical and psychological dependence, so careful monitoring of dependence is essential during long-term use. Due to the inclusion of acetaminophen, patients with impaired liver function should consult a doctor before taking this medication and avoid concomitant use of other acetaminophen products. Particularly, individuals who metabolize this drug rapidly due to genetic factors may be at higher risk for respiratory depression and should be cautious, and this drug should not be administered to pediatric patients. Patients with sleep apnea or hypoxia should continually monitor symptom changes as symptoms may worsen after taking this drug. This medication can lead to hyponatremia, so elderly patients or those at risk for hyponatremia should regularly check their blood sodium levels. Ensure not to exceed the recommended dosage while taking this medication and be cautious not to use it alongside other medications with similar ingredients. Abrupt discontinuation may result in withdrawal symptoms such as anxiety, insomnia, and sweating, so it is safe to taper off gradually under the direction of a physician. Drowsiness or dizziness may occur when driving or operating machinery, so caution is necessary if these symptoms are present. In case of overdose, severe side effects such as respiratory depression, seizures, and liver damage may occur; seek medical attention immediately if suspected.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by coughing+fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, vision disturbances, paralysis, urination.

Mild side effects

  • Decreased appetite
  • insomnia
  • depression
  • dizziness
  • headache
  • drowsiness
  • nausea
  • vomiting
  • constipation
  • dry mouth
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  • diarrhea
  • indigestion
  • abdominal pain
  • abdominal discomfort
  • flatulence
  • itching
  • sweating
  • rash
  • fatigue
  • flushing
  • hypoglycemia
  • anxiety
  • irritability
  • mood instability
  • euphoria
  • decreased libido
  • sleep disturbances
  • confusion
  • disorientation
  • excitability
  • abnormal dreams
  • drug abuse
  • hallucinations
  • withdrawal syndrome
  • migraine
  • sedation
  • sensory loss
  • tremors
  • sensations.

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a sealed container that does not allow air to enter, ideally at a temperature between 1 and 30 degrees Celsius. This way, the efficacy of the drug can be maintained for an extended period.

Appearance and packaging

Appearance

Pale yellow oblong film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.