Donecept 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

Adults: Donepezil Hydrochloride is administered at a dose of 5 mg once daily before bedtime. The dose of 5 mg should be given for 4 to 6 weeks, and after evaluating clinical response during this period, it can be increased to 10 mg. When increasing to a daily dose of 10 mg, caution should be exercised regarding gastrointestinal adverse reactions. Underweight female patients over 85 years of age should not exceed a daily dose of 5 mg and require careful monitoring.

Child dose

Children: There is no experience with the use in children.

This medication contains Donepezil Hydrochloride Hydrate as the active ingredient and is used for the improvement of Alzheimer's-type dementia symptoms. First of all, this medication should not be used in certain patients. For example, individuals allergic to this medication or its ingredients, women who are pregnant or may become pregnant, and women who are breastfeeding should not take this medication. Furthermore, patients with heart diseases or conduction disorders, history of gastric ulcers or those taking non-steroidal anti-inflammatory drugs, patients with a history of asthma or obstructive pulmonary diseases, and those with extrapyramidal disorders such as Parkinson's disease should use this medication cautiously, and thorough monitoring by a physician is necessary. This medication can cause various side effects such as bradycardia, arrhythmia, exacerbation of peptic ulcers, bronchoconstriction, and motor disturbances, so if any unusual symptoms occur, immediate consultation with a healthcare professional is advised. Additionally, symptoms such as dizziness, drowsiness, hallucinations, insomnia, nausea, vomiting, diarrhea, appetite loss, headache, and fatigue may appear while taking this medication, so caution is necessary. Patients with heart diseases may require electrocardiogram monitoring, and particular care should be taken when used in combination with related medications due to the associated risk of QT interval prolongation. Women who are pregnant or breastfeeding are advised not to use this medication, and if use is necessary, it is recommended to consult a specialist and discontinue breastfeeding. This medication has not been established as safe for children and should not be used by them. Furthermore, caution should be exercised when driving or operating machinery, as dizziness or drowsiness may occur. This medication may interact with other drugs, so if you are taking other medications, you must inform your healthcare professional. In case of overdose, symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, and you should immediately visit a medical institution for appropriate treatment. Finally, this medication should be stored out of reach of children, and transferring it to another container is not recommended as it may adversely affect quality.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• fainting
• bradycardia
• heart block
• QT interval prolongation
• myocardial infarction
• heart failure

Mild side effects

Loss of appetite, nausea, vomiting, diarrhea, headache, fatigue, drowsiness, dizziness, insomnia, fever, myalgia, urinary incontinence, anxiety, skin rash, thrombocytopenia, hematological abnormalities, dehydration, hyperlipidemia, hypertension, hypotension, palpitations, anemia, frequent urination, tremor, aggressive behavior, sweating, confusion, drowsiness, petechiae, skin itching, eczema, edema, hematological and lymphatic abnormalities, vasodilation, weight loss, muscle cramps, arthritis, and others.

This medication should be stored in a sealed container to prevent air infiltration and kept at a temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the efficacy of the medication.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle