Mupainjeong

Adult dose

Children and adults over 12 years: The dosage should be adjusted based on the patient's level of pain and therapeutic response. An initial dosage of 2 tablets is recommended, with subsequent intervals of at least 6 hours, ensuring not to exceed 8 tablets per day. Administer the lowest effective dose for the shortest possible duration. Do not administer this medication for longer than necessary, and in cases where prolonged administration is required due to the nature and severity of the illness, ensure regular monitoring to confirm the need for continuous use of this medication. Elderly: Administer the usual adult dosage, noting that the elimination half-life of tramadol increases by 17% with oral administration in patients over 75 years, thus the medication should be dosed at minimum intervals of 6 hours. Renal impairment: For patients with moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. Administration is not recommended for patients with severe renal impairment (creatinine clearance of less than 10 mL/min). Tramadol is removed very slowly during hemodialysis and filtration, so re-administration post-dialysis is not necessary to maintain effect. Hepatic impairment: Consider extending the dosing interval for patients with moderate hepatic impairment. Do not administer this medication to patients with moderate hepatic impairment.

This medication may cause liver damage in individuals who regularly consume more than three glasses of alcohol daily, so it is essential to consult a doctor or pharmacist before use. If a rash or other hypersensitivity reaction occurs during treatment, discontinue use immediately, as severe skin conditions may rarely occur. The ingredients in this medication may induce seizures; therefore, patients with a history of seizures or those at high risk for seizures should use with caution. Rarely, life-threatening allergic reactions may occur during treatment; if any unusual symptoms arise, notify healthcare professionals immediately. Patients with acute and severe bronchial asthma may experience a worsening of respiratory depression when taking this medication; it should be administered in a medically equipped facility. Taking this medication concurrently with alcohol or central nervous system depressants can result in severe drowsiness, respiratory depression, or coma, so extreme caution is advised when combining. Patients with head injuries or increased intracranial pressure may experience worsening of symptoms with this medication; use carefully. This medication can cause psychological and physical dependence; patients should follow the doctor's instructions for extended use, and those at risk for dependence should be especially cautious. Patients with poor liver function must consult their doctor before using this medication and should avoid simultaneous use with other acetaminophen products. Patients with certain genetic backgrounds may metabolize the active ingredients of this medication rapidly, increasing the risk of respiratory depression; dosage adjustments and monitoring are required. Children under 12 years of age and certain post-surgical children should not take this medication, and adolescents aged 12 to 18 should avoid it if risk factors are present. Patients with sleep apnea or hypoxemia must continuously monitor for worsening symptoms while on this medication, adjusting or discontinuing the dosage as necessary. Elderly patients or those at risk of hyponatremia should be closely monitored for symptoms of hyponatremia while on this medication. This medication should not be administered to patients with specific diseases or those on certain drugs, especially severe respiratory depression, head injury, or severe liver and kidney dysfunction. Do not exceed the recommended dose when taking this medication, and avoid using it concurrently with other analgesics, as abrupt discontinuation may lead to withdrawal symptoms. Additionally, this medication may cause drowsiness and dizziness, so caution is required when driving or operating machinery. In case of overdose, there is a risk of severe respiratory depression, seizures, liver damage, etc., so immediate emergency treatment is required, including the administration of an antidote if necessary. This medication should be stored out of reach of children, and care should be taken to prevent drug misuse.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizure, confusion of consciousness, visual disturbances, paralysis, urinary retention

Mild side effects

• Loss of appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

Store this medication in a tightly sealed container to prevent air from entering, in a cool place at room temperature below 25 degrees Celsius. This storage method helps maintain the medication's effectiveness for a longer time.

Appearance

Light yellow, rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle