Viewing nowCombinationMufine Semi Tablet
Acetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Daehan New Pharm Co., Ltd.

MFDS item code 200804942 · Notified 2008.04.30 · Insurance code 669904800
Relief of moderate to severe acute and chronic pain
This medication is used to relieve acute and chronic pain that is moderate to severe.
Children aged 12 and above and adults should adjust the dosage according to the patient's pain level and treatment response. The initial dosage is 4 tablets, with subsequent doses administered at least 6 hours apart. The total daily dosage should not exceed 16 tablets. This medication should be administered at the lowest effective dose for the shortest duration necessary. In cases requiring long-term administration, the need for continued use should be assessed through regular monitoring.
Children aged 12 and above should be administered the same dosage as adults.
This medication may put a strain on the liver, so individuals who consume alcohol regularly above a certain amount should consult a doctor or pharmacist before taking it. If any unusual reactions such as rashes or blisters appear on the skin during treatment with this drug, it should be discontinued immediately, and medical attention should be sought. One of the ingredients, tramadol, may induce seizures; therefore, caution is advised for individuals with a history of seizures or a high risk of seizures. In particular, taking tramadol with certain specific antidepressants or narcotic analgesics may increase the risk of seizures. When administering this drug to patients with severe asthma, medical supervision is required due to the risk of breathing difficulties. Concurrent use of this medication with alcohol or central nervous system depressants may result in severe drowsiness, respiratory depression, or coma, hence co-administration should be avoided. Patients with brain injury or elevated intracranial pressure should be cautious when taking this medication, as symptoms may worsen. This product may cause physical and psychological dependence; hence, long-term use should be adjusted by a doctor. Individuals with impaired liver function must consult a doctor before taking this medication and should not take it with other acetaminophen-containing drugs to minimize the risk of liver damage. Individuals with certain genetic traits may metabolize the ingredients of this medication rapidly, which may pose serious side effect risks such as respiratory depression. It is safer not to use this medication in children under 12 years of age or adolescents under 18 years who have undergone a specific surgery. Patients with sleep apnea or respiratory-related diseases should periodically check for symptom exacerbation while taking this medication. Drowsiness or dizziness may occur during treatment, thus caution is required when driving or operating machinery. In case of overdose, severe respiratory depression, seizures, liver damage, and other dangerous symptoms may arise, so it is crucial to adhere to the prescribed dosage.
Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the oral/ocular mucosa, shortness of breath or breathing difficulties, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme drowsiness, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, and urinary retention.
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly sealed container to prevent exposure to air and moisture and is best stored in a cool place below room temperature (25 degrees).
Light yellow oblong film-coated tablets
30 tablets/bottle, 300 tablets/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Viewing nowCombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Daehan New Pharm Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Yuyoung Pharmaceutical Co., Ltd.
CombinationAcetaminophen 325mg · Tramadol Hydrochloride 37.5mg
Tablet · Prescription medication · Combination
Youyoung Pharmaceutical Co., Ltd.
CombinationTramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
Korea Pharmaceutical Co., Ltd.
CombinationTramadol Hydrochloride 37.5mg · Acetaminophen 325mg
Tablet · Prescription medication · Combination
Korea United Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Shinpoong Pharmaceutical Co., Ltd.
CombinationAcetaminophen 325mg · Tramadol Hydrochloride 37.5mg
Tablet · Prescription medication · Combination
Sinphong Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Albozen Korea Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.