Stariset Tablet (Acetaminophen, Tramadol Hydrochloride)

Adult dose

Children aged 12 years and older and adults: The dosage should be adjusted based on the patient’s level of pain and therapeutic response. It is recommended to administer 2 tablets as the initial dose, after which the dosing interval should be at least 6 hours, but not to exceed 8 tablets per day. Administer the lowest effective dose for the shortest duration possible. Avoid prolonged administration beyond what is necessary, and in cases where long-term administration is needed due to the nature and severity of the illness, regular monitoring should be conducted to evaluate the necessity of continued treatment.

Child dose

Children aged 12 years and older and adults: The dosage should be adjusted based on the patient’s level of pain and therapeutic response. It is recommended to administer 2 tablets as the initial dose, after which the dosing interval should be at least 6 hours, but not to exceed 8 tablets per day.

This drug may stress the liver; individuals who regularly consume more than three drinks a day must consult a physician or pharmacist. Otherwise, liver damage may occur. While rare, acetaminophen can cause severe skin reactions; if rashes or allergic reactions occur, discontinue use immediately. Exceeding the recommended dose of tramadol may increase the risk of seizures, particularly when taken in combination with certain antidepressants or narcotics. There is a risk of respiratory depression while taking this medication, thus special caution is needed for patients with acute asthma or respiratory conditions, and it should be administered under medical supervision. Taking this drug with alcohol or sedatives may lead to severe drowsiness, respiratory depression, or coma, so co-administration should be avoided. Patients with elevated intracranial pressure or head injuries may experience worsening symptoms while using this medication. This medication may lead to physical and psychological dependence; therefore, close monitoring for dependency is necessary during long-term use. Individuals with impaired liver function must consult a physician before using this drug, as there is a risk of hepatotoxicity; care must be taken not to exceed the daily maximum dosage. Patients with certain genotypes may metabolize this drug rapidly, increasing the risk of respiratory depression, necessitating dosage adjustment and symptom monitoring. This drug should not be used in children under 12 years old or in adolescents under 18 years old who have undergone tonsillectomy or adenoidectomy. Patients with sleep apnea or hypoxemia may experience exacerbated symptoms while taking this drug and should be carefully monitored. Those at risk of hyponatremia should have their serum sodium levels checked regularly while taking this drug. Individuals allergic to any ingredient in this medication, those with central nervous system drug abuse, severe respiratory depression, head injuries, or taking MAO inhibitors should not take this drug. When using this medication, adhere strictly to the recommended dosages and avoid using other acetaminophen or tramadol products concurrently. Sudden discontinuation may lead to withdrawal symptoms; gradual tapering under medical guidance is necessary. There are many interactions with this drug and other medications so it's crucial to inform healthcare providers of any concomitant medications, especially when used with antidepressants, antibiotics, anticoagulants, or central nervous system depressants. Caution is advised when driving or operating machinery as drowsiness and dizziness may occur. In cases of overdose, serious side effects such as respiratory depression, seizures, or liver damage may occur; strict adherence to dosages is essential, and immediate medical attention should be sought in emergencies. Store in a safe place out of the reach of children to prevent misuse or abuse of the medication.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/nasal mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormality accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urinary issues.

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

Store this medication in a tightly sealed container to prevent air exposure, and it is best kept at room temperature, below 25 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Pale yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle