Lesezale Tablet (Levocetirizine Hydrochloride)

Adult dose

Adults: orally take 1 tablet (5mg as levocetirizine hydrochloride) once daily, regardless of meals. In patients with renal impairment, adjust the dose based on renal function (Creatinine clearance (CLCR)). - Mild (50 ≤ CLCR < 80): 1 tablet once daily. - Moderate (30 ≤ CLCR < 50): 1 tablet every 2 days. - Severe (10 ≤ CLCR < 30): 1 tablet every 3 days.

Child dose

Children aged 6 and older: orally take 1 tablet (5mg as levocetirizine hydrochloride) once daily, regardless of meals. Adjust dose according to age and symptoms.

This medication should not be used by patients who have allergies to certain ingredients or who have shown hypersensitivity to hydoxyzine or piperazine derivatives. It should not be administered to patients with severely impaired renal function or those undergoing hemodialysis. Pregnant women or women who might become pregnant, as well as nursing mothers, should not take this medication. It should not be given to infants under 1 year of age, and children under 6 years should be given liquid form instead of tablets. This tablet contains lactose, so patients with lactose intolerance or certain genetic lactose metabolism disorders should avoid taking it. Patients with kidney or liver problems and the elderly should use this medication cautiously, as it may increase blood concentration. This medication may cause CNS side effects such as drowsiness, headache, dizziness, and fatigue. Gastrointestinal symptoms may include nausea, loss of appetite, abdominal pain, and diarrhea. Rarely, heart rhythm abnormalities or blood-related adverse reactions, rash, and blurred vision may occur. After taking this medication, drowsiness or fatigue may occur, so caution is required when engaging in tasks that require attention, such as driving or operating machinery. Taking with alcohol or central nervous system depressants may intensify drowsiness; therefore, it is best to avoid doing so. This medication should be used with caution in patients with urinary excretion disorders, especially in cases of spinal cord injury or prostatic enlargement. Taking it with food may slow down absorption speed, but it does not affect the total absorption amount. It is safer for pregnant women or nursing mothers not to take this medication. For children under 12 years, safety and efficacy have not been sufficiently confirmed, so caution is needed; especially, it should not be given to infants under 1 year. The elderly may have increased blood concentration due to decreased kidney function, so they should start with a low dose and observe the condition while adjusting it. It is advisable to temporarily discontinue this medication before allergy testing, as it does not affect testing results. In case of overdose, symptoms such as drowsiness or anxiety may occur, and since there is no specific antidote, symptomatic treatment should be received. This medication is not well removed by hemodialysis, so care is needed in case of overdose.

Serious side effects

Urticaria, severe swelling (edema), angioedema, anaphylactic shock, severe rash accompanied by high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, respiratory distress, asthma attack, respiratory abnormalities accompanied by cough and fever, increased blood pressure, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, severe swelling or urinary abnormalities.

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• malaise
• fatigue
• dizziness
• heaviness in the head
• excitement
• thirst

This medication is sensitive to light and should be stored in a container that blocks light. Moreover, it is recommended to store at room temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication.

Appearance

White or pale yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle