Medication info
Hanlim Alprazolam Tablet 0.5 mg

Hanlim Alprazolam Tablet 0.5 mg

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.5mg / 1 tablet
Manufacturer / importer
Hanlim Pharmaceutical Co., Ltd.
Appearance
Purple oval tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200803405 · Approved 2008.03.27 · Insurance code 645303420

Summary

Main use
Relief of symptoms of anxiety (including anxiety disorders with depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
To obtain optimal benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse reactions. The risk of dependence may increase with dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible duration, and frequently reassess the need to continue treatment. ○ Adults 1. Initiate treatment with alprazolam 0.25-0.5㎎ per dose, 3 times daily, with a maximum dose of 4㎎ per day. For older adults, patients with hepatic impairment, and debilitated patients, initiate treatment with 0.25㎎ per dose, 2-3 times daily. Reduce the dose if adverse reactions occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine orally in 3 divided doses per day. If increasing the dose, increase it gradually to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For older adults, initiate treatment with 0.4㎎ per dose, 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this medicine is 0.5㎎. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose reduction may be required.

Ingredients

Manufacturer
Hanlim Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety (including anxiety disorders with depression), panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety
  • tension
  • depression
  • sleep disturbances
  • panic disorder
View approved original text

This medication is used for the treatment of anxiety disorders and for the short-term alleviation of anxiety symptoms, as well as the alleviation of anxiety symptoms associated with depression. It also helps improve anxiety, tension, depressive symptoms, and sleep disturbances due to psychosomatic disorders such as gastric or duodenal ulcers, irritable bowel syndrome, and autonomic dysfunction. In addition, it is effective for the treatment of panic disorder. This medication is used for the alleviation and treatment of various anxiety-related conditions and symptoms.

How to take

Adult dose

To obtain optimal benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse reactions. The risk of dependence may increase with dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible duration, and frequently reassess the need to continue treatment. ○ Adults 1. Initiate treatment with alprazolam 0.25-0.5㎎ per dose, 3 times daily, with a maximum dose of 4㎎ per day. For older adults, patients with hepatic impairment, and debilitated patients, initiate treatment with 0.25㎎ per dose, 2-3 times daily. Reduce the dose if adverse reactions occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine orally in 3 divided doses per day. If increasing the dose, increase it gradually to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For older adults, initiate treatment with 0.4㎎ per dose, 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this medicine is 0.5㎎. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose reduction may be required.

Precautions

This medication is a benzodiazepine and has a depressant effect on the central nervous system. Taking it in combination with narcotics can lead to severe sedation, respiratory depression, coma, or death, so it should always be used in the minimum effective dose and for the shortest duration of time under a doctor's guidance. The risk of abuse and dependence exists, so it should be used under proper supervision by a physician. It is especially dangerous to use in combination with other central nervous system depressants or alcohol. This medication should not be given to patients with certain conditions, such as acute angle-closure glaucoma, severe myasthenia gravis, severe respiratory failure, severe liver failure, or in late stages of pregnancy. Additionally, patients with genetic issues like lactose intolerance should avoid it. Caution is necessary for patients with reduced cardiac, liver, or kidney function, those with organic brain disorders, elderly patients, and patients with sleep apnea; it is also important to take care if allergic to any dyes included in this medication. Drowsiness, decreased concentration, and ataxia may occur as side effects, so dangerous activities such as driving or operating machinery should be avoided. Regular blood tests and liver function tests are advised for long-term use, and sudden discontinuation can cause withdrawal symptoms or seizures, so the dosage should be reduced gradually. Patients with depression or psychotic symptoms should use this medication cautiously, as there may be an increased risk of suicidal thoughts or behaviors requiring careful monitoring. When combined with other medications, there may be interactions that enhance the effect of this medication or increase side effects, so it is essential to inform a physician or pharmacist, and dosage adjustments may be necessary. During pregnancy, especially in later stages, it may pose risks to the fetus, and during breastfeeding, it may affect the baby, so use should be avoided if possible or breastfeeding should be suspended. The safety and efficacy for children under 18 years have not been established, so use is not recommended. In elderly patients, side effects may manifest more readily, so it is prudent to start with low doses and use with caution. In cases of overdose, severe drowsiness, motor control issues, coma, and respiratory depression may occur, necessitating immediate treatment, and appropriate emergency measures should be undertaken as per a doctor's advice. This medication should be stored out of reach of children and kept in its original container to prevent misuse or deterioration of quality.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • tremors
  • convulsions
  • agitation
  • increased muscle rigidity
  • sleep disturbances
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  • hallucinations
  • anxiety
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • hostility
  • obsessive thoughts
  • drowsiness
  • headaches
  • depression
  • confusion
  • disorientation
  • decreased libido
  • anxiety
  • nervousness
  • increased libido
  • mania
  • hallucinations
  • anger
  • anxiety
  • drug dependence
  • hypomania
  • aggression
  • hostility
  • abnormal thoughts
  • movement disorders
  • drug abuse
  • memory impairment
  • speech disturbance
  • dizziness
  • balance disorder
  • cooperation disorder
  • attention deficit
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone abnormalities
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • gastrointestinal disturbances
  • hepatitis
  • abnormal liver function
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity reactions
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • irregular menstruation
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • elevated intraocular pressure
  • drowsiness
  • mild headaches
  • depression
  • headaches
  • confusion
  • insomnia
  • nervousness
  • fainting
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • nasal congestion
  • excitement
  • tremors
  • dermatitis
  • rash
  • increased appetite
  • decreased appetite
  • urinary disturbances
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infections
  • involuntary movement disorders
  • decreased libido
  • confused state
  • single muscle contractions
  • weakness
  • abnormal muscle tone
  • anxiety
  • disinhibition
  • sensory abnormalities
  • polyuria
  • vascular movement disorders
  • derealization
  • abnormal dreams
  • fear
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • weight gain
  • weight loss
  • urinary disturbances
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infections
  • seizures
  • hallucinations
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • disorientation
  • ataxia
  • balance disorders
  • difficulty concentrating
  • excessive sleep
  • somnolence
  • muscle weakness
  • elevated liver enzymes
  • Stevens-Johnson syndrome
  • gynecomastia
  • galactorrhea
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • fatigue
  • falls
  • drowsiness
  • decreased attention
  • decreased concentration
  • decreased reflex motor ability
  • insomnia
  • involuntary movement disorders
  • cognitive impairment
  • confused state
  • anxiety
  • fatigue
  • irritability
  • memory impairment
  • coordination disorders
  • weakness
  • memory impairment
  • depression
  • confused state
  • nausea
  • vomiting
  • diarrhea
  • decreased salivation
  • weight loss
  • loss of appetite
  • sweating
  • tachycardia
  • blurred vision
  • seizures
  • hallucinations
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • Stevens-Johnson syndrome
  • gynecomastia
  • galactorrhea
  • ataxia
  • excessive sedation
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a light-blocking, sealed container, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way can help maintain the medication's efficacy and prevent degradation.

Appearance and packaging

Appearance

Purple oval tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.