Glywon Tablet 4 mg (Glimepiride)

Adult dose

1. Monotherapy - Initial dose: Start with 1 mg of Glimepiride once daily. - Dose increase: May increase by 1 mg every 1-2 weeks. - General maximum dose: No additional effect when administered over 4 mg; however, if necessary, can increase to a maximum of 6 mg or 8 mg. - If 4 mg daily is ineffective, consider switching to insulin therapy or combination. 2. Combination therapy - When used with insulin: Once daily

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or in a comatose state. Patients with a history of allergic reactions to this medication, its components, or sulfonylureas should also avoid use. There is no experience using this medication in patients with severely impaired liver or kidney function; switching to insulin therapy is recommended in such cases. Women who are pregnant or may become pregnant, as well as nursing mothers, should avoid this medication for safety. Patients with severe infections, those undergoing surgery, or patients with severe trauma may require insulin therapy and should avoid this medication. If gastrointestinal disturbances such as diarrhea or vomiting occur, caution should be exercised due to the risk of hypoglycemia from inadequate food absorption. During the first week of taking this medication, the risk of hypoglycemia is heightened, so blood glucose levels should be closely monitored. Especially in the elderly, those with poor nutritional status or irregular eating habits, or individuals who consume alcohol frequently, the risk of hypoglycemia increases. Caution is also necessary when there is an imbalance between exercise and carbohydrate intake or when eating patterns change. Patients with weak liver or kidney function, those with other endocrine disorders, or in cases of overdose also face increased risk of hypoglycemia. Interactions with other medications may affect blood sugar control, so it is essential to consult a doctor or pharmacist. This medication has the effect of lowering blood sugar, which can lead to the appearance of hypoglycemia symptoms, including headache, severe hunger, nausea, fatigue, drowsiness, confusion, and decreased consciousness. Hypoglycemia should be treated promptly by consuming sugar, and severe symptoms require immediate medical attention. Additionally, while taking this medication, temporary blurred vision, digestive symptoms, liver function abnormalities, blood abnormalities, and allergic reactions may occur, necessitating caution. If allergic symptoms such as hives or difficulty breathing appear, inform a doctor immediately. This medication should be taken regularly for blood sugar control, and dietary and exercise therapies should be accompanied. In case of hypoglycemia, quickly consuming sugar is important, as artificial sweeteners are not effective for hypoglycemia treatment. In situations of severe stress, surgery, or infections, blood sugar control may become difficult, so temporary switching to insulin therapy may be necessary. When used in combination with other medications, this medication may influence blood sugar control, so all medications being taken should be communicated to healthcare providers, and attention should be given to drug interactions. Careful monitoring is especially required when taken with beta-blockers, certain antibiotics, or steroids. Women who are pregnant or breastfeeding should not use this medication as it may affect the fetus or newborn, and insulin therapy should be considered if necessary. The safety and efficacy of this medication have not been adequately established in children and adolescents under 18 years of age. In the elderly, there may be a reduction in kidney function, so dose adjustments should be made cautiously. In cases of overdose, severe hypoglycemia may occur, requiring immediate medical attention and appropriate treatment; if hypoglycemia symptoms appear, sugar should be consumed quickly. This medication should be stored out of reach of children and maintained in its original container to preserve its quality.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, hypotension, shock, severe allergic reactions, Stevens-Johnson syndrome, liver dysfunction (cholestasis, jaundice), hepatitis, hemolytic anemia, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, thrombocytopenic purpura, severe hypoglycemia (loss of consciousness, coma, convulsions), severe allergic reactions, significant changes in blood parameters, liver failure

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• reduced agility or activity

This medication should be stored in a tightly sealed container to prevent air or moisture exposure. The recommended storage temperature is between 1 to 30 degrees Celsius at room temperature. Proper storage helps maintain the effectiveness and safety of the medication.

Appearance

Blue or light blue oblong tablets

Package unit

30 tablets/bottle, 100 tablets/bottle