Medication info
Duo-skujeong 5/10 mg (Amlodipine Besilate, Atorvastatin Calcium Hydrate)

Duo-skujeong 5/10 mg (Amlodipine Besilate, Atorvastatin Calcium Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium Hydrate›10.85mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
현대약품(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 200802596 · Approved 2008.03.06 · Insurance code 642001620

Summary

Main use
(Hypertension, Angina) Improvement of myocardial ischemia and risk reduction of (cardiovascular diseases)
Who takes it
Adults
Adult dose
This medication is administered only to adults, and the dosing should be individualized for each patient based on the efficacy and tolerability of amlodipine/atorvastatin. Amlodipine (Es-Amlodipine): 5 (2.5) mg orally once daily, with a maximum increase to 10 (5) mg daily based on patient response. Atorvastatin: - For patients with primary hypercholesterolemia and mixed dyslipidemia: recommended initial

Ingredients

Manufacturer
현대약품(주)

Efficacy & effects

(Hypertension, Angina) Improvement of myocardial ischemia and risk reduction of (cardiovascular diseases)

  • Hypertension
  • fixed obstruction of coronary arteries
  • vascular spasm
  • vasoconstriction
  • myocardial ischemia
  • angina
  • multiple risk factors for coronary heart disease
  • retinopathy
  • albuminuria
  • type 2 diabetes
  • primary hypercholesterolemia
  • mixed dyslipidemia
View approved original text

This medication is used for patients who need to take both amlodipine and atorvastatin. Amlodipine improves cardiovascular diseases such as hypertension and angina, and helps reduce the risk of hospitalization and vascular revascularization in patients with coronary heart disease. Atorvastatin reduces the risk of cardiovascular diseases such as myocardial infarction, stroke, and angina, and is effective in treating hypercholesterolemia and dyslipidemia. The combination of these two drugs is used to improve overall cardiovascular health by controlling not only hypertension but also blood lipid levels.

How to take

Adult dose

This medication is administered only to adults, and the dosing should be individualized for each patient based on the efficacy and tolerability of amlodipine/atorvastatin. Amlodipine (Es-Amlodipine): 5 (2.5) mg orally once daily, with a maximum increase to 10 (5) mg daily based on patient response. Atorvastatin: - For patients with primary hypercholesterolemia and mixed dyslipidemia: recommended initial

Precautions

It is very important that this medication is not administered to certain patients. For example, it should not be used in patients who are allergic to this medication or similar medications, severely impaired liver function, pregnant or nursing women, patients with muscle disease, severe aortic stenosis, patients in shock, and patients within one month after myocardial infarction. Additionally, patients with very poor kidney function, elderly patients, alcoholics, patients with a history of liver disease should use this medication with caution. Patients who may have muscle-related issues should have their muscle enzyme levels checked prior to administration. This medication usually has good tolerability, but may occasionally cause mild side effects such as flushing, edema, dizziness, headache, and dyspepsia. Serious side effects such as liver dysfunction, myalgia, and allergic reactions can rarely occur, so if any unusual symptoms appear, immediate consultation with a physician is necessary. This medication is not to be used in pregnant women or women who may become pregnant, and appropriate contraception must be practiced during administration. Nursing mothers should also discontinue breastfeeding while taking this medication. This medication interacts with many other drugs, so especially if taking drugs metabolized in the liver or certain antibiotics, antifungals, immunosuppressants, etc., it is essential to inform the physician. Dosing adjustments or monitoring may be needed when combined with other medications. In case of overdose, hypotension, arrhythmias, and in severe cases, shock may occur, requiring immediate emergency treatment. This medication is not removed by kidney dialysis, so special treatment may be necessary in case of overdose. The safety of this medication for children and the elderly has not been sufficiently verified, so caution is needed when using it in these age groups. Finally, this medication should be kept out of reach of children, and transferring it to another container should be avoided.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), severe allergic reactions, severe rash with fever, blisters, skin peeling, pain of oral/eye mucous membranes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues with coughing and fever, yellowing of the skin or eyes (jaundice), extreme malaise, liver abnormalities (jaundice), sudden and severe headache, lightning headache, seizures, consciousness disorders

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • lethargy
  • pain
  • weight change
  • hypotension
  • vasculitis
  • muscle tension
  • sensory impairment
  • paresthesia
  • peripheral neuropathy
  • syncope
  • dysgeusia
  • tremor
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hypertrophy
  • gingival hyperplasia
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps
  • myalgia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent the ingress of air or moisture and should be kept at room temperature between 1 to 30 degrees Celsius. Storing it this way can maintain the medication's efficacy and safety.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.