Bastia Tablets 10 mg (Donepezil Hydrochloride)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. If sleep disturbances such as strange dreams, nightmares, or insomnia occur, consider taking the medication in the morning. Normalcy is reached after 15 days of administration, and 5 mg should be administered for 4 to 6 weeks. Based on clinical response evaluation, the dose may be increased up to 10 mg. When increasing to 10 mg per day, observe for gastrointestinal adverse reactions. In underweight individuals and female patients over 85 years old: special monitoring is needed as adverse reactions are more common. Underweight elderly women should not exceed 5 mg per day.

Child dose

There is no experience of use in children.

This medication contains Donepezil Hydrochloride as its active ingredient and is mainly used for the improvement of cognitive function in patients with Alzheimer's type dementia. Firstly, this medication should not be administered to certain patients. For example, individuals allergic to this medication or its components, pregnant women or those who may become pregnant, and patients with lactose intolerance or specific genetic metabolic disorders should not take this medication. Additionally, this medication should be used with caution in patients with heart disease, a history of peptic ulcers or those currently taking non-steroidal anti-inflammatory drugs, patients with a history of asthma or chronic obstructive pulmonary disease, and patients with extrapyramidal disorders such as Parkinson's disease. Caution is also necessary for individuals allergic to the ingredient Tartrazine included in this medication. Various adverse reactions may occur while taking this medication. Cardiac-related issues may include bradycardia, heart block, and myocardial infarction, while gastrointestinal side effects may involve gastric ulcers or gastrointestinal bleeding. Reports of liver dysfunction, cerebrovascular disorders, motor function impairments, serious muscle problems, respiratory difficulties, acute pancreatitis, acute renal failure, and unexplained sudden death have also been documented. Psychiatric issues may include hallucinations, agitation, aggressive behavior, anxiety, insomnia, depression, and confusion, while neurological abnormalities may involve fainting, dizziness, and seizures. This medication particularly affects the cardiovascular system and may increase the risk of bradycardia or cardiac arrhythmias, so patients with heart disease should always consult a physician before taking it. Furthermore, this medication may impact liver and kidney function, so regular testing may be required. Caution is advised during driving or operating machinery while taking this medication, as dizziness or fatigue may increase the risk of accidents. It is advisable for women who are pregnant or breastfeeding to avoid taking this medication; if it must be taken, they should consult with an expert before proceeding. This medication may interact with several other drugs. Particularly, when taken with drugs that are metabolized in the liver, the efficacy of this medication may change, so it is crucial to inform your doctor or pharmacist if you are taking other medications. In case of overdose, severe symptoms such as nausea, vomiting, sweating, bradycardia, hypotension, respiratory depression, and convulsions may appear, and immediate medical attention should be sought for appropriate treatment. Lastly, this medication should be kept out of the reach of children and transferring it to another container should be avoided to maintain its quality and safety.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, gastrointestinal bleeding, peptic ulcers, hepatitis, liver dysfunction, jaundice, cerebral seizures, cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders, neuroleptic malignant syndrome, rhabdomyolysis, respiratory distress, acute pancreatitis, acute renal failure, unexplained sudden death, serious allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness)

Mild side effects

• Nausea
• vomiting
• diarrhea
• decreased appetite
• headache
• fatigue
• dizziness
• insomnia
• drowsiness
• muscle pain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and is best kept at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy and prevents deterioration.

Appearance

Yellow round film-coated tablets

Package unit

[Domestic Use] 30 Tablets/Bottle, 100 Tablets/Bottle [Export Use] 30 Tablets (10 Tablets/PTP x 3)