Risendro Tablets 35 mg (Risendronic Acid Sodium 2.5 Hydrate)

Adult dose

As Risendronic Acid Sodium, take one dose of 35 mg orally once a week. Food can interfere with absorption, so take it at least 30 minutes before breakfast or at least 2 hours before or after food intake. Take it upright with a sufficient amount of pure water (170-230 mL) and do not chew or suck on the tablet. Do not lie down for at least 30 minutes after taking this medication.

Child dose

Safety and efficacy for children under 18 years of age have not been established.

This medication can irritate the gastric and esophageal mucosa, so caution should be exercised when prescribed to patients with upper gastrointestinal diseases such as gastritis, esophagitis, or ulcers. After taking the medication, do not lie down for at least 30 minutes and take it with a sufficient amount of water to reduce esophageal irritation. Patients with esophageal motility disorders, such as esophageal stricture or achalasia, those with hypocalcemia, pregnant women, or women who may become pregnant, and patients with severe renal impairment should not use this medication. This medication contains lactose, so it should not be taken by patients with lactose intolerance. During treatment, it is important to ensure adequate intake of calcium and vitamin D, and those with hypocalcemia or vitamin D deficiency should be treated before taking this medication. As a bisphosphonate, it has a rare risk of serious side effects such as osteonecrosis of the jaw or atypical femoral fractures, so patients should pay attention to oral health and consult a physician if experiencing pain in the legs. When taking this medication, avoid foods or supplements containing divalent cations (calcium, magnesium, iron, etc.) at the same time, and space out the administration by a sufficient time interval before and after taking it to ensure optimal absorption. Pregnant or breastfeeding women are advised not to take this medication, and if they are currently taking it, they should consult with a physician. Safety and efficacy have not been established for children under 18 years of age. In the case of overdose, hypocalcemia may occur; therefore, if symptoms arise, the patient should notify healthcare personnel immediately and may require calcium supplementation. This medication should be stored out of reach of children and should not be transferred to another container for safety.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing
• Heartburn, cold sweat, paleness
• Severe allergic reactions
• Severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa
• Severe skin adverse reactions
• Shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever
• Respiratory problems
• Yellowing of the skin or eyes (jaundice), profound lethargy
• Liver abnormalities (jaundice)
• Sudden and severe

Mild side effects

• Back pain
• accidental injury
• pain
• abdominal pain
• flu-like symptoms
• headache
• weakness
• pain in the neck
• chest pain
• hypertension

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best kept at room temperature between 1°C and 30°C. Doing so will maintain the efficacy of the medication and prevent degradation.

Appearance

Pale orange rectangular film-coated tablets

Package unit

4 tablets/box [(4 tablets/PTP) × 1]