Tracon Tablet (Itraconazole Solid Dispersion)

Adult dose

For improved absorption, this medicine should preferably be administered immediately after a meal. Vulvovaginal candidiasis: Administer itraconazole 200 mg twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. Pityriasis versicolor: Administer 200 mg once daily for 7 days. Tinea corporis, tinea cruris: Administer 100 mg once daily for 15 days. Tinea manuum (interdigital type), tinea pedis (interdigital type): Administer 100 mg once daily for 15 days. Tinea manuum (palms), tinea pedis (soles): Administer 100 mg once daily for 30 days, or 200 mg twice daily for 7 days. Oral candidiasis: Administer 100 mg once daily for 15 days. Fungal keratitis: Administer 200 mg once daily for 21 days. Intermittent treatment of onychomycosis: Administer 200 mg twice daily for 1 week, followed by a 3-week treatment-free period; this constitutes one cycle. Administer up to 2 cycles if only the fingernails are infected, and up to 3 cycles if the toenails are infected. Continuous treatment of onychomycosis: Administer 200 mg once daily for 3 months. In patients with impaired immune function, such as those with neutropenia, AIDS, or an organ transplant, the oral bioavailability of this medicine may be reduced; if necessary, increase the dose twofold. Aspergillosis: 200mg once daily for 2～5 months. For invasive or disseminated disease, increase to 200mg twice daily. Candidiasis: 100～200mg once daily for 3 weeks～7 months. Cryptococcal meningitis: 200mg twice daily for 2 months～1 year. Maintenance therapy: 200mg once daily. Paracoccidioidomycosis: 100mg once daily for 6 months. To improve absorption, do not administer this medicine with food. Oral and esophageal candidiasis: Take 200 mg (20 mL) per day in 1～2 divided doses for 1 week. If there is no effect after 1 week, continue for 1 more week. Oral and esophageal candidiasis resistant to fluconazole: Take 200～400 mg (20～40 mL) per day in 1～2 divided doses for 2 weeks. If there is no effect after 2 weeks, continue for 2 more weeks. Do not use 400 mg per day for more than 14 days, even if symptoms have not improved. Prevention of fungal infections: Administer 5 mg per kg of body weight per day in 2 divided doses.

This drug can be dangerous for patients with reduced heart function, especially those with congestive heart failure, so it should not be used in these patients. If signs of heart failure appear during treatment with this drug, administration should be stopped immediately and a doctor should be consulted. Patients with allergies to this drug or those who have had hypersensitivity reactions to its components should not use it. Additionally, this drug can cause serious side effects when taken with certain medications, so patients must inform their doctor or pharmacist about all medications they are currently taking. It is safest for women who are pregnant or may become pregnant, and those who are breastfeeding, to avoid this medication. Patients with impaired liver or kidney function should exercise caution when using this drug and regular liver function tests are recommended. This drug can rarely cause severe liver damage, allergic reactions, neurological abnormalities, and hearing loss, so medical consultation should be sought if symptoms appear. Caution is needed when driving or operating machinery, as dizziness, blurred vision, and hearing loss may occur. This drug may not be well absorbed in conditions of low acidity, so if taking medications that reduce acidity, it may help to take it with acidic beverages. In case of overdose, specific antidotes are not available, so immediate medical treatment should be sought. Use in children, the elderly and patients with compromised immune functions should be evaluated after consulting a doctor.

Headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, taste disorder, sensory impairment, paresthesia, tinnitus, constipation, diarrhea, dyspepsia, bloating, vomiting, liver dysfunction, hyperbilirubinemia, itching, rash, urticaria, polyuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusional state, peripheral neuropathy, dizziness, drowsiness, tremors, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, voice disorders, cough, gastrointestinal disorders, hepatic failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, kidney dysfunction, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased blood urea, increased gamma-glutamyl transferase, increased liver enzymes, abnormal urinalysis, increased white blood cell count, increased eosinophils, anemia, vascular edema, serum sickness, angioedema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, temporary or permanent hearing loss, ventricular ectopic beats, atrial block, palpitations, increased bowel motility, belching, glossitis, stomatitis, abdominal lumbar pain, pancreatitis, increase in serum total protein, increase in total bilirubin, increase in LAP, appetite loss, malaise, dark urine, increased liver enzyme levels, mucocutaneous syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive urinary protein test, positive urinary glucose test, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, increased serum triglycerides, flushing, increased serum uric acid, increased serum potassium, serum sickness, angioedema, anaphylactic response, hypertriglyceridemia, tremors, visual impairment, congestive heart failure, dyspnea, pancreatitis, significant hepatotoxicity, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, erythema multiforme, exfoliative dermatitis, leukocytoclastic vasculitis, hair loss, photosensitivity, increased serum creatine phosphokinase

This drug should be stored in a tightly sealed container to prevent air and moisture from entering, and should be kept at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

Round film-coated tablet, white or light yellow

Package unit

30 tablets/bottle, 100 tablets/bottle