Ulset Semi-Tablet

Adult dose

For children and adults aged 12 and over: Dosage should be adjusted according to the severity of the patient's pain and treatment response. An initial dose of 4 tablets is recommended, and subsequent doses should be at least 6 hours apart, not to exceed 16 tablets in one day. The lowest effective dose should be administered for the shortest duration possible. Ensure that this medication is not taken for longer than necessary, and in cases where prolonged treatment is required due to the nature and severity of the condition, regular monitoring should be conducted to confirm the continued necessity of this medication. Elderly The usual adult dose should be administered. However, in patients over 75 years of age taking tramadol orally, the elimination half-life of tramadol is increased by 17%, so doses should be administered at an interval of at least 6 hours. Patients with renal impairment For patients with moderate renal impairment (creatinine clearance of 10-30 ml/min), the dosing interval should be extended to 12 hours. For patients with severe renal impairment (creatinine clearance of less than 10 ml/min), administration is not recommended. Tramadol is removed very slowly during blood dialysis and filtration, thus there is no need for re-administration of this medication to maintain pain relief post-dialysis. Patients with liver impairment For patients with moderate liver impairment, careful consideration should be given to extending the dosing interval. Administration is not advised in patients with severe liver impairment.

This medication can put a strain on the liver, so individuals who regularly consume more than three glasses of alcohol a day should consult a doctor or pharmacist before use. If any adverse reactions such as skin rashes or itching occur during the use of this medication, discontinue immediately and consult a healthcare professional. Due to the risk of seizures, patients with a history of seizures or risk factors for seizures should use this medication with caution, as the risk may increase when combined with certain antidepressants or other narcotic analgesics. There can be rare but serious allergic reactions, so symptoms such as hives and difficulty breathing require immediate treatment. Patients with severe bronchial asthma may experience increased respiratory depression when taking this medication, and therefore it should only be administered under careful monitoring in a medically equipped environment. Taking this medication with alcohol or central nervous system depressants can intensify sedation and respiratory depression, so it should be avoided or used very cautiously. Patients with head injuries or increased intracranial pressure should be cautious as symptoms may worsen with this medication. This medication has the potential to cause psychological and physical dependence, thus dependence should be periodically checked in cases of long-term use. Patients with impaired liver function should consult a doctor before taking this medication, and should not exceed the recommended dosage due to the risk of liver damage from acetaminophen. Particularly, individuals who metabolize this medication rapidly due to genetic factors are at higher risk for side effects, so dosage adjustments and careful monitoring are necessary. This medication should not be administered to children under 12 or adolescents under 18 who have undergone certain surgical procedures; it is also advisable to avoid use in cases of sleep apnea. This medication can cause hyponatremia, so especially elderly patients or those with risk factors should routinely monitor their serum sodium levels. Patients with allergies to this medication's components, severe respiratory depression, head injuries, or those on certain medications should not take this medication. Caution is advised during driving or operating machinery as drowsiness or dizziness may occur during treatment. Overdose can lead to serious respiratory depression, seizures, or liver damage, so the prescribed dosage must be strictly adhered to, and if overdose is suspected, immediate medical attention is necessary. This medication should be stored out of reach of children to prevent accidental ingestion or misuse.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eyes mucus membranes, difficulty breathing or shortness of breath, asthma attacks, respiratory disturbances accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion of consciousness, visual disturbances, paralysis, urination difficulties

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, and is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage prolongs the effectiveness of the medication.

Appearance

Pale yellow rectangular film-coated tablet

Package unit

<For domestic use> - 30 tablets/bottle,<For domestic use> - 100 tablets/bottle,<For domestic use> - 300 tablets/bottle,<For export> - 100 tablets/box[(10 tablets/PTP x 10)]