Medication info

Actimin Injection (Fursultiamine Hydrochloride)

Prescription medicationInjections
Ingredient · strength
Fursultiamine Hydrochloride›5.46mg / 1mL
Manufacturer / importer
동국제약(주)
Appearance
A brown ampule containing a colorless or pale yellow liquid
Packaging
10 ampules/box [(10 milliliters/ampule × 10)]
Approval status
Active

MFDS item code 200712504 · Notified 2007.11.15

Summary

Main use
Preventive and therapeutic effects for neuropathy and cardiac disorders related to vitamin B1 deficiency and metabolic disorders
Who uses it
Adults
Adult dosage
As fursultiamine, it is usually injected subcutaneously, intramuscularly, or intravenously at a dose of 5 to 100 mg per day for adults. Adjustments can be made according to the symptoms.

Ingredients

Manufacturer
동국제약(주)

Efficacy & effects

Preventive and therapeutic effects for neuropathy and cardiac disorders related to vitamin B1 deficiency and metabolic disorders

  • Vitamin B1 deficiency
  • wasting diseases
  • hyperthyroidism
  • Wernicke's encephalopathy
  • beriberi heart disease
  • neuropathy
  • myalgia
  • arthralgia
  • peripheral neuritis
  • peripheral nerve paralysis
  • myocardial metabolic disorders
  • constipation
View approved original text

This medication is used to prevent and treat symptoms and conditions caused by vitamin B1 deficiency. It helps alleviate various symptoms such as neuropathy, myalgia, and peripheral neuritis, especially when vitamin B1 intake is insufficient. Additionally, it is used in the treatment of serious conditions such as Wernicke's encephalopathy or beriberi heart disease. It can also assist pregnant women, nursing mothers, or patients with hyperthyroidism, who have an increased demand for vitamin B1 and find it difficult to intake. However, it is important not to use it for an extended period without purpose, as its effectiveness is only established in cases of presumed vitamin B1 deficiency or metabolic disorders. This medication is used to improve several symptoms related to vitamin B1 deficiency.

Dosage and Administration

Adult dosage

As fursultiamine, it is usually injected subcutaneously, intramuscularly, or intravenously at a dose of 5 to 100 mg per day for adults. Adjustments can be made according to the symptoms.

Precautions

This medication is in a glass ampule form, and when opening the injection container, glass pieces may fall into the medication, which can cause adverse reactions. Therefore, extreme caution must be exercised when opening the ampule. Extra caution is also necessary when administering to children and the elderly. Patients who have had allergic reactions to this medication or its components should not use it. Patients with a history of drug allergies should be cautious when using this medication. Although rare, serious adverse reactions such as shock can occur when using this medication; therefore, if symptoms such as a sudden drop in blood pressure, chest pain, or shortness of breath occur, administration should be stopped immediately and appropriate treatment should be sought. Additionally, if allergic symptoms such as rashes appear, the use of the medication should be stopped. Gastrointestinal symptoms may rarely include nausea, vomiting, stomatitis, and occasional diarrhea. Headaches or frequent urination have also been reported occasionally. To reduce vascular pain during injection, it should be administered as slowly as possible. When using the injection solution, it is safe not to reuse any leftover medication to prevent bacterial contamination. When opening the ampule, position the marked part facing up and carefully apply force to the opposite end to cut it, and clean the upper part of the ampule with alcohol cotton to prevent foreign substance contamination. This medication should be stored in a secure place out of the reach of children, and transferring it to another container could lead to accidents or degradation of the medication’s quality, so it must be stored in its original container.

Side effects and when to seek care immediately

Serious side effects

  • Shock
  • hypotension
  • chest pain
  • dyspnea

Mild side effects

  • Rash
  • nausea
  • vomiting
  • stomatitis
  • diarrhea
  • headache
  • frequent urination

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that can block light, at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the medication’s efficacy and safety.

Appearance and packaging

Appearance

A brown ampule containing a colorless or pale yellow liquid

Package unit

10 ampules/box [(10 milliliters/ampule × 10)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.