Osonel Tablet (Risedronate Sodium)

Adult dose

Adults: Administer 35 mg of risedronate sodium orally once weekly. Elderly: No dose adjustment is necessary in elderly patients (over 60 years) because the bioavailability and pharmacodynamics of this drug are similar to those in younger people. Patients with renal impairment: No dose adjustment is necessary in patients with a creatinine clearance of 30 mL/min or higher. This drug is contraindicated in patients with severe renal impairment and a creatinine clearance of less than 30 mL/min. Food interferes with the absorption of this drug. For adequate absorption, take it at least 30 minutes before breakfast or at least 2 hours apart from food or beverages at any time of day. To help this drug reach the stomach readily and reduce the possibility of esophageal irritation, take it in an upright position with a sufficient amount of plain water (170 ∼ 230 mL). Taking it with other beverages, including mineral water, may reduce absorption. Do not chew or suck this drug because of the possibility of oropharyngeal ulceration. Patients should not lie down for at least 30 minutes after taking it. If a patient forgets to take the drug on the scheduled day, take it the next morning when remembered. Resume the next dose on the originally scheduled day. Do not take 2 tablets on the same day.

Child dose

The safety and efficacy of this drug in children under 18 years of age have not been established.

This medication can cause irritation to the stomach and esophagus, so patients with upper gastrointestinal diseases such as gastritis, esophagitis, or esophageal ulcers should use it with caution. It should be taken with a sufficient amount of water, and patients should remain upright for at least 30 minutes after taking to reduce esophageal irritation. This medication should not be administered to patients with esophageal stricture or achalasia, patients with hypocalcemia, pregnant or breastfeeding women, or patients with severe renal impairment. Additionally, patients allergic to lactose contained in this medication should not take it. It's important to have adequate calcium and vitamin D intake during treatment, and any hypocalcemia or other bone metabolic disorders should be treated beforehand. There is a possibility of rare side effects such as osteonecrosis of the jaw, so consultation with a doctor is necessary before any dental procedures, and oral hygiene should be maintained. If pain occurs in the legs or hip region during treatment, consult a doctor immediately, and consider the risk of atypical fractures with long-term use. This medication may interfere with the absorption of foods or medications containing calcium, magnesium, or iron, so be mindful of the timing and intervals of intake. Women who are pregnant or may become pregnant should not take this medication, and breastfeeding women should stop either the medication or breastfeeding. Safety and efficacy have not been established in children under 18 years of age, so it should not be used. In case of overdose, hypocalcemia may occur, so immediate medical attention is necessary, and calcium supplementation may be required if needed. This medication should be kept in a safe place out of reach of children and should not be transferred to other containers.

• Esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• bleeding
• infection
• lumbago
• accidental injury
• pain

This medication should be stored in a tightly closed container to prevent air and moisture exposure. It is best to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Light orange oval film-coated tablet

Package unit

4 tablets/PTP