Medication info
Desmin Tablet 0.2 mg (Desmopressin Acetate)

Desmin Tablet 0.2 mg (Desmopressin Acetate)

Prescription medicationTabletOral
Ingredient · strength
Desmopressin Acetate›0.2mg / 1 tablet
Manufacturer / importer
Dongkook Pharmaceutical Co., Ltd.
Appearance
White, convex, round tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 200710856 · Notified 2007.09.28 · Insurance code 653400070

Summary

Main use
Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)
Who takes it
Adults · Children
Adult dose
Treatment of nocturia associated with nocturnal polyuria (adults only) : Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg; if the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue administration if there is no clinical effect within 4 weeks after dose determination. Initiating treatment with this medicine is not recommended in patients aged 65 years or older. In elderly patients who require treatment, closely monitor serum sodium levels, etc. (See 5. General Precautions under Precautions for Use.)
Child dose
Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following a treatment-free period of at least 1 week.

Ingredients

Manufacturer
Dongkook Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)

  • Primary nocturnal enuresis
  • nocturia
  • nocturia symptoms
View approved original text

This medication is primarily used for the treatment of primary nocturnal enuresis in children aged 5 years and older and is effective in alleviating nocturia symptoms associated with nocturia in adults. It helps improve sleep disturbances and inconveniences in daily life that may arise from nocturia.

How to take

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) : Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg; if the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue administration if there is no clinical effect within 4 weeks after dose determination. Initiating treatment with this medicine is not recommended in patients aged 65 years or older. In elderly patients who require treatment, closely monitor serum sodium levels, etc. (See 5. General Precautions under Precautions for Use.)

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following a treatment-free period of at least 1 week.

Precautions

This medication regulates the balance of water in the body. When taking this medication, fluid intake should be restricted to a level that causes thirst. Excessive fluid intake can lower sodium levels in the blood, which may lead to coma or severe side effects. Patients with allergies to this medication or certain kidney diseases, heart failure, or hyponatremia should not take it. Patients with hypertension, cardiovascular diseases, chronic kidney diseases, women who are pregnant or may become pregnant, as well as children and the elderly, should take this medication only under careful medical supervision. Symptoms such as headache, nausea, weight gain, and seizures may occur during treatment, so if any abnormal symptoms arise, immediate consultation with healthcare professionals is necessary. Fluid intake should be restricted from 1 hour before taking this medication to 8 hours after. It is important to limit fluid intake to a maximum of 0.5 liters during kidney function tests. Especially for elderly patients aged 65 and over, the risk of hyponatremia is higher, so regular blood tests should be conducted to monitor sodium levels. This medication may interact with other drugs, so it is essential to inform the healthcare provider about any other medications currently being taken, particularly antidepressants, diuretics, corticosteroids, and non-steroidal anti-inflammatory drugs, as caution is needed when taking these together. Women who are pregnant or breastfeeding should consult a doctor before taking this medication, and it is recommended to discontinue breastfeeding while on this medication. Overdose may result in severe symptoms such as headache, nausea, seizures, and loss of consciousness, and immediate medical treatment should be sought in such cases. This medication does not affect the ability to drive or operate machinery and does not cause significant disruptions in daily life.

Side effects

  • coma
  • convulsions
  • weight gain
  • severe water intoxication
  • hyponatremia
  • allergic reactions
  • emotional disturbances
  • headache
  • abdominal pain
  • nausea
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  • allergic skin reactions
  • dizziness
  • peripheral edema
  • frequent urination
  • thirst
  • anaphylaxis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This will help preserve the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

White, convex, round tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.