Desmin Tablet 0.1 mg (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg; if the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue administration if there is no clinical effect within 4 weeks after dose determination. Initiating treatment with this medicine is not recommended in patients aged 65 years or older. In elderly patients who require treatment, closely monitor serum sodium levels, etc. (See 5. General Precautions under Precautions for Use.)

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following a treatment-free period of at least 1 week.

This medication helps regulate the body's fluid balance. During the course of taking this medication, fluid intake should be limited to the point of thirst. Excessive fluid intake may lower blood sodium levels, potentially leading to coma or serious side effects. Certain patients should not take this medication. For example, individuals allergic to this drug or any of its components, those with severe renal impairment, patients with certain heart conditions, those taking diuretics, and individuals with genetic issues such as lactose intolerance should not use this medication. Additionally, caution is advised for individuals with hypertension, cardiovascular diseases, chronic kidney diseases, pregnant women or those who may become pregnant, as well as children and the elderly. They may have a higher risk of electrolyte imbalance or fluid retention. Side effects such as hyponatremia, headache, nausea, weight gain, and seizures may occur when taking this medication, so if symptoms arise, immediate consultation with healthcare providers is necessary. Fluid intake must be strictly limited during treatment, particularly for one hour before dosing and for eight hours after dosing, to avoid excessive fluid consumption. In cases of reduced renal function, this restriction period may be prolonged. This medication may interact with other medications, so if taking antidepressants, diuretics, steroids, anticonvulsants, or other drugs, it is essential to inform the doctor or pharmacist. Use during pregnancy should be cautious due to the possibility of uterine contractions. If breastfeeding, it is advisable to discontinue breastfeeding. Overdose may present symptoms such as headache, nausea, seizures, and loss of consciousness; in such cases, seek immediate medical assistance. If necessary, medication dosage should be reduced, and fluid intake should be limited, and in severe cases, diuretics may be required.

• coma
• convulsions
• weight gain
• severe water intoxication
• hyponatremia
• allergic reactions
• emotional disturbances
• headache
• abdominal pain
• nausea

This medication may be sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

White, round tablet

Package unit

30 tablets/bottle