Medication info
Lexifin Tablet (Doxofylline)

Lexifin Tablet (Doxofylline)

Prescription medicationTabletOral
Ingredient · strength
Doxofylline›400mg / 1 tablet
Manufacturer / importer
Daehwa Pharmaceutical Co., Ltd.
Appearance
White rectangular tablets
Packaging
30 tablets/bottle, 300 tablets/bottle, 100 tablets (10 tablets/PTP x 10)
Approval status
Active

MFDS item code 200710105 · Approved 2007.09.04 · Insurance code 645600830

Summary

Main use
Treatment of bronchial asthma and chronic obstructive bronchitis
Who takes it
Adults
Adult dose
Adults: Administer 400 mg of doxofylline orally 2 ~ 3 times daily.

Ingredients

Manufacturer
Daehwa Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of bronchial asthma and chronic obstructive bronchitis

  • Bronchial asthma
  • chronic obstructive pulmonary disease
View approved original text

This medication is used for respiratory diseases such as bronchial asthma and chronic obstructive pulmonary disease.

How to take

Adult dose

Adults: Administer 400 mg of doxofylline orally 2 ~ 3 times daily.

Precautions

This medication should not be administered to certain patients. Individuals with an allergy to this medication, its components, or other xanthine derivatives should not take it. Patients with acute myocardial infarction, those with low blood pressure, and women who are breastfeeding should also avoid using this medication. Various side effects may occur when taking this medication, such as nausea, vomiting, abdominal pain, headache, insomnia, and irregular heartbeats, so caution is advised. In case of overdose, serious arrhythmias or seizures may occur, so the dosage must be strictly adhered to. Patients with liver, heart, lung, or kidney diseases or infections, as well as those taking certain antibiotics or other medications may experience altered drug metabolism, necessitating dosage adjustment and blood concentration monitoring. Patients with a history of hypertension, heart disease, hyperthyroidism, and those who are elderly should use this medication with particular caution; especially the elderly may require a reduced dosage. This medication may increase toxicity if taken simultaneously with caffeinated beverages or foods, sympathomimetics like ephedrine, and should not be co-administered with these substances. Pregnant women should only take this medication if the therapeutic benefit outweighs the potential risk, as its safety has not been sufficiently established; it is advisable for breastfeeding women not to take this medication. Children, particularly infants, may be more sensitive to this medication and should be used with caution. In the event of an overdose, complications related to the heart or seizures may occur, and immediate consultation with healthcare professionals is necessary; as there is no specific antidote, treatment should be symptomatic. This medication should be kept out of the reach of children, and transferring it to other containers may lead to quality degradation or accidents, so caution is advised. This medication does not pose a risk of tolerance or addiction, and it does not affect driving or operating machinery.

Side effects

  • Nausea
  • vomiting
  • upper abdominal pain
  • headache
  • irritability
  • insomnia
  • tachycardia
  • extrasystole
  • rapid breathing
  • hyperglycemia
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  • proteinuria
  • severe arrhythmia
  • seizures
  • dyspepsia
  • heartburn
  • headache
  • dizziness
  • chest pain
  • chest fullness
  • generalized weakness
  • fever
  • chills
  • fatigue
  • abdominal distension
  • swelling
  • joint pain
  • pain
  • leg pain
  • back pain
  • generalized edema
  • hernia
  • tuberculosis
  • facial flushing
  • tremors
  • chest tightness
  • chest discomfort
  • chest wall pain
  • peripheral edema
  • increased blood pressure
  • heart palpitations
  • palpitations worsening
  • arrhythmia
  • premature beats
  • myocardial infarction
  • sleep disturbance
  • appetite loss
  • anxiety
  • decreased appetite
  • lethargy
  • excitability
  • depression
  • tremor delirium
  • suicidal tendencies
  • dyspnea
  • worsening dyspnea
  • upper respiratory infection
  • cough
  • runny nose
  • hemoptysis
  • pneumonia
  • pulmonary congestion
  • hyperventilation
  • rapid breathing
  • phlegm disorders
  • increased phlegm viscosity
  • shortness of breath
  • bronchitis
  • shallow breathing abnormalities
  • nosebleed
  • tonsillitis
  • blood-stained phlegm
  • throat pain
  • increased phlegm
  • lung damage
  • alveolitis
  • throat pain
  • urinary retention
  • hematuria
  • facial swelling
  • urinary abnormalities
  • itching
  • hives
  • sweating
  • maculopapular rash
  • hair loss
  • seborrheic dermatitis
  • papules
  • scaly rash
  • skin peeling
  • dry mouth
  • abdominal pain
  • upper abdominal pain
  • abdominal discomfort
  • abdominal pain
  • gastric ulcer
  • gastritis
  • esophageal pain
  • lip ulcer
  • constipation
  • dysphagia
  • diarrhea
  • hematemesis
  • toothache
  • tongue pain
  • hiccups
  • dry throat
  • gas reflux
  • muscle twitching
  • muscle micro-tremors
  • sensory abnormalities
  • skin tingling
  • distal sensory abnormalities
  • skin sensory abnormalities
  • difficulty awakening
  • voice changes
  • focal seizure
  • hypersensitivity
  • rigidity
  • paralysis
  • hemianopia
  • polyarthralgia
  • non-inflammatory joint swelling
  • myalgia
  • myopathy
  • joint abnormalities
  • neck and shoulder pain
  • limb weakness
  • leg fractures
  • polymyalgia
  • vertebral fractures
  • weight gain
  • weight loss
  • hypoglycemia
  • starvation weakness
  • thirst
  • lung carcinoma
  • uterine fibroids
  • thyroid tumors
  • tinnitus
  • hearing loss
  • double vision
  • eye pain
  • loss of taste
  • taste disturbances
  • shingles
  • septal deviation
  • inflammatory edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly closed container. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius to ensure the medication's effectiveness is preserved safely for a long time.

Appearance and packaging

Appearance

White rectangular tablets

Package unit

30 tablets/bottle, 300 tablets/bottle, 100 tablets (10 tablets/PTP x 10)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.