Nutrasset Semi Tablet

Adult dose

Children aged 12 and above and adults: Dosage is adjusted based on the patient's pain level and treatment response. An initial dose of 4 tablets is recommended, and subsequent doses should be spaced at least 6 hours apart, not exceeding 16 tablets in one day. The effective lowest dose should be administered for the shortest time possible. Avoid prolonged use of this medication beyond necessity, and if prolonged administration is needed due to the disease's nature and severity, regular monitoring should be conducted to assess the need for continued use of this medication. Elderly Administer the standard adult dose. However, in elderly patients aged 75 or older, the half-life of tramadol following oral administration increases by 17%, so doses should be administered at intervals of at least 6 hours. Patients with renal impairment Moderate renal impairment patients (creatinine clearance of 10-30 mL/min) should have their dosing intervals extended to 12 hours. Administration is not recommended for patients with severe renal impairment (creatinine clearance of less than 10 mL/min). Tramadol is eliminated very slowly by hemodialysis, so re-administration of this medication post-dialysis is not necessary to maintain analgesic effects. Patients with hepatic impairment In patients with moderate hepatic impairment, careful consideration should be given to extending the dosing interval. Administration is not recommended for patients with severe hepatic impairment.

Child dose

Children aged 12 and above and adults: Dosage is adjusted based on the patient's pain level and treatment response. An initial dose of 4 tablets is recommended, and subsequent doses should be spaced at least 6 hours apart, with a maximum of 16 tablets per day.

This medication may burden the liver, so individuals who regularly consume more than three glasses of alcohol daily should consult a doctor or pharmacist. If a rash or hypersensitivity reaction occurs during the use of this medication, discontinue immediately and seek medical attention. Individuals with a history of seizures or at risk of seizures should exercise caution while on this medication due to the potential risk of seizures. Anaphylactic reactions, which can be life-threatening, may rarely occur with this medication, so anyone experiencing allergies should inform healthcare professionals immediately. Patients with acute and severe asthma can experience difficulty breathing while taking this medication, and it should only be used under medical supervision. Combining this medication with alcohol or central nervous system depressants can lead to severe sedation or respiratory depression, so such combinations should be avoided. Patients with head injuries or elevated intracranial pressure should be cautious as respiratory depression from this medication may worsen their condition. This medication can cause mental and physical dependence; hence, it should be taken under medical guidance for prolonged periods. Patients with impaired liver function must consult a doctor before taking this medication and should not exceed the recommended dosage. Rapid metabolizers with the CYP2D6 genotype may metabolize the active ingredient of this medication quickly, increasing the risk of respiratory depression, and should be cautious. This medication should not be administered to children under 12 years of age or adolescents under 18 years of age after certain surgeries. Patients with sleep apnea or at risk for hypoxia should continuously monitor for symptom exacerbation while on this medication. Elderly patients or those at risk for hyponatremia should monitor their serum sodium levels while on this medication. This medication may interact with certain drugs, so if taking other medications, it is essential to inform healthcare professionals. Pregnant or breastfeeding women must consult a doctor before using this medication, as it may affect the baby, especially during breastfeeding. Caution is needed as this medication can cause drowsiness or dizziness when driving or operating machinery.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound fatigue, liver dysfunction (jaundice), sudden and severe headache, thunderclap headache, seizures

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a sealed, airtight container and kept at room temperature between 1 and 30 degrees Celsius. This helps maintain the medication's efficacy and prevents deterioration.

Appearance

Light yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle