Nutrasset Tablet

Adult dose

For children over 12 years old and adults: The dosage should be adjusted according to the level of pain and therapeutic response. A recommended initial dose is 2 tablets, and subsequent doses should be spaced at least 6 hours apart, but not to exceed 8 tablets per day. The lowest effective dose should be given for as short a duration as possible. Avoid prolonged use of this medication beyond what is necessary, and if prolonged use is needed due to the nature and severity of the disease, regular monitoring should be carried out to determine whether continued use of this medication is needed. Elderly Administer the usual adult dosage; however, in patients over 75, the oral half-life of tramadol is increased by 17%, so it should be administered at intervals of at least 6 hours. Renal Impairment For moderate renal impairment patients (creatinine clearance of 10-30 mL/min), increase the dosing interval to 12 hours. Administration is not recommended for those with severe renal impairment (creatinine clearance below 10 mL/min). Tramadol is removed very slowly during hemodialysis and filtration, thus it is not necessary to readminister the medication after dialysis to maintain analgesic effect. Liver Impairment In cases of moderate liver impairment, consider cautiously extending the dosing interval. This medication should not be administered to patients with severe liver impairment.

Child dose

For children over 12 years old and adults: The dosage should be adjusted according to the level of pain and therapeutic response. A recommended initial dose is 2 tablets, and subsequent doses should be spaced at least 6 hours apart, but not to exceed 8 tablets per day.

This medication may put a strain on the liver; therefore, those who regularly consume more than three glasses of alcohol a day should consult with a doctor or pharmacist before taking it. This medication can rarely cause serious skin allergic reactions; if a rash or hypersensitivity occurs, discontinue use immediately. The ingredients in this medication can increase the risk of seizures; caution is required if you have a history of seizures or are taking medications that increase seizure risk. Patients with impaired respiratory function or severe bronchial asthma may experience life-threatening respiratory depression when taking this medication; it should be taken in an environment where medical personnel can monitor the patient. Taking this medication in conjunction with alcohol or central nervous system depressants can lead to severe sedation, respiratory depression, coma, and even death; it is advisable to avoid combination or use the minimum dosage for a short period if necessary. Patients with elevated intracranial pressure or head injuries may be at risk of increased brain pressure when taking this medication; caution is needed. This medication can lead to physical and psychological dependence; therefore, prolonged use should be closely monitored for signs of dependency. Patients with compromised liver function should consult a doctor before taking this medication, as its components may stress the liver. Patients with certain genetic traits (CYP2D6 ultra-rapid metabolizers) may have elevated concentrations of the active metabolite, increasing the risk of severe respiratory depression; dosage adjustment and close monitoring are necessary. This medication should not be given to children under 12 years old and adolescents under 18 years old who have undergone tonsillectomy or adenoidectomy. Adolescents aged 12 to 18 should avoid use if they have specific risk factors. This medication can exacerbate sleep apnea and hypoxemia; if symptoms change, consideration should be given to adjusting or discontinuing the dosage. Elderly patients or those at risk of hyponatremia should be closely monitored for the occurrence of hyponatremia during treatment with this medication. This medication should not be given to patients allergic to certain components, those with central nervous system drug dependence, those with severe respiratory depression, those with head injuries, those on MAO inhibitors, those with severe liver, kidney, or heart dysfunction, nursing mothers, children under 12 years old, adolescents under 18 years old after specific surgeries, and patients with aspirin-induced asthma. This medication increases the risk of seizures and respiratory depression when combined with other central nervous system depressants, opioids, or antidepressants; caution is warranted, and minimal doses should be used for the shortest duration necessary. Drowsiness or dizziness may occur during use, so caution should be exercised when driving or operating machinery. In case of overdose, serious respiratory depression, seizures, liver damage, and other severe complications may occur, so do not exceed the recommended dosage, and seek medical attention immediately if overdose is suspected. This medication should be kept out of the reach of children, and access to it should be restricted to prevent misuse or abuse.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Loss of appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. Additionally, it is recommended to store it at room temperature between 1°C and 30°C. This helps to maintain the effectiveness of the drug.

Appearance

Pale yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle