Azithromycin Tablet 250 Milligrams (Azithromycin Hydrate)

Adult dose

This medication is administered once daily. As with most antibiotics, it should be taken 1 hour before a meal or 2 hours after a meal (capsules only). ○ Adults 1) Sexually transmitted infection caused by Chlamydia trachomatis: Administer 1g (potency) of azithromycin as a single dose. 2) Other indications - 3-day regimen: Administer 500mg (potency) of azithromycin once daily for 3 days [total dose 1.5g (potency)]. - 5-day regimen: Administer 500mg (potency) as a single dose on the first day. From the second day, administer 250mg (potency) once daily for 4 days [total dose 1.5g (potency)]. ○ Older adults Administer the same dose and dosage regimen as for adults.

Child dose

○ Children (45Kg or more): Administer the same dose as for adults.

This drug is a macrolide antibiotic, and although allergic reactions are rare, they can be serious, so if hypersensitivity occurs, administration should be stopped immediately and treatment sought. During the use of this drug, severe enteritis, such as diarrhea caused by Clostridium difficile, may occur; therefore, careful observation is required if diarrhea symptoms appear. This drug should not be administered to patients with hypersensitivity to certain antibiotics or patients taking ergot alkaloids. It should be used with caution in patients with severely impaired renal function and severe liver dysfunction, and if signs of liver dysfunction appear, drug use should be stopped immediately. During treatment, gastrointestinal adverse reactions such as nausea, vomiting, diarrhea as well as hearing loss, skin rash, and various side effects may occur; thus, if symptoms arise, consultation with a healthcare professional is necessary. As with other antibiotics, there is a risk of superinfection caused by non-susceptible organisms; therefore, infection symptoms should be monitored closely. In patients with heart disease or who are at high risk of QT interval prolongation, there is a risk of cardiac arrhythmias; hence, it should be used with caution. Patients with myasthenia gravis may experience exacerbation of symptoms when taking this medication, requiring careful consideration. This drug may interact with certain medications, so if there are other medications being taken, it is essential to inform healthcare providers. During pregnancy, safety for the fetus has not been established, so it should be used only when necessary, and in breastfeeding situations, careful judgment is needed as the drug may be transmitted through breast milk. Elderly patients may be at a higher risk of experiencing cardiac arrhythmias, thus requiring special attention during use. In cases of overdose, treatment should be supportive with general symptomatic management, and it is crucial to keep this drug out of the reach of children. Furthermore, medications should be stored in their original containers to maintain quality.

Angioedema, anaphylaxis, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reactions accompanied by eosinophilia and systemic symptoms, diarrhea, nausea, vomiting, loose stools, abdominal discomfort, abdominal distension, liver dysfunction, rash, urticaria, candidiasis, vaginitis, thrombocytopenia, leukopenia, neutropenia, shock, symptoms of anaphylaxis, loss of appetite, aggressive reactions, neurosensitization, agitation, anxiety, dizziness, seizures, headache, hyperactivity, sensory disturbances, drowsiness, sensory loss, syncope, altered or lost taste/smell, hearing loss, tinnitus, hearing impairment, palpitations, ventricular tachycardia, arrhythmia, QT prolongation, Torsades de pointes, hypotension, dyspepsia, constipation, membranous enterocolitis, pancreatitis, pyloric stenosis, tongue discoloration, hepatitis, jaundice, cholestatic jaundice, hepatic necrosis, hepatic failure, itching, photosensitivity reactions, edema, urticaria, angioedema, erythema multiforme, arthralgia, rhabdomyolysis, myalgia, feelings of exhaustion, elevated CK, increased myoglobin in blood and urine, interstitial nephritis, acute renal failure, weakness, fatigue, malaise, fever, cough, dyspnea, abnormal chest X-ray findings, eosinophilia

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is important to keep it at a cool temperature below 25 degrees Celsius to maintain its effectiveness.

Appearance

White rectangular film-coated tablets

Package unit

30 tablets (10 tablets/PTP x 3), 100 tablets/bottle