DomenTaksok Tablet 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

Administer 5 mg once daily before bedtime as Donepezil Hydrochloride. For 4-6 weeks, administer a dose of 5 mg, and after evaluating clinical response during this period, it can be increased to 10 mg. When increasing to 10 mg daily, monitor for gastrointestinal side effects closely. This medicine is an orodispersible tablet that can be placed on the tongue to dissolve and taken with or without water.

This drug contains Donepezil Hydrochloride as its main ingredient and is used to alleviate the symptoms of Alzheimer's disease. First, this drug should not be used by individuals allergic to Donepezil Hydrochloride or any of its components, or by women who are pregnant or may become pregnant, or those who are breastfeeding. Patients with heart disease or cardiac conduction disorders should use this drug with caution as it may slow heart rate or cause arrhythmias. Patients currently on non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should observe their condition closely since this drug may increase gastric acid secretion and worsen symptoms. Patients with asthma or chronic obstructive pulmonary disease should be cautious as this drug may cause bronchial muscle contraction and increased mucus secretion, worsening symptoms. Patients with extrapyramidal disorders such as Parkinson's disease should use this drug cautiously as it may affect the nervous system, worsening symptoms or causing new ones. While taking this drug, serious side effects such as fainting, bradycardia, heart block, gastrointestinal bleeding, liver dysfunction, seizures, muscle pain, and difficulty breathing may occur, and any abnormal symptoms should be consulted with a doctor immediately. Additionally, this drug may cause various side effects such as diarrhea, nausea, vomiting, loss of appetite, dizziness, insomnia, headache, and fatigue, so inform healthcare providers if any symptoms arise. This drug can affect liver and kidney function, so regular testing may be required. Care should be taken during activities requiring attentiveness, such as driving or operating machinery, due to potential dizziness or fatigue. This drug may interact with other medications, and patients taking other drugs should inform their healthcare providers. It is generally advised that women who are pregnant or breastfeeding do not use this drug unless absolutely necessary and under the guidance of a professional. Safety in children has not been established; therefore, it should not be used in pediatric patients. In case of overdose, symptoms may include nausea, vomiting, sweating, decreased heart rate, and respiratory depression, so immediate medical attention should be sought. This drug is to be taken as an orodispersible tablet that should be placed on the tongue and swallowed with saliva or water, and it must be kept out of reach of children. Storage should be done in a tightly sealed container that is not exposed to air, and it should be kept at room temperature between 1 to 30 degrees Celsius. This way, the medication's efficacy can be safely maintained.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash associated with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), systemic weakness, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, decreased urine output

Mild side effects

• Headache
• dizziness
• nausea
• vomiting
• diarrhea
• loss of appetite
• fatigue
• insomnia
• tremors
• drowsiness

This drug should be stored in a tightly sealed container that is not exposed to air, and it must be kept at room temperature between 1 to 30 degrees Celsius. Doing so will help safely maintain the efficacy of the drug.

Appearance

White round orodispersible tablet

Package unit

30 tablets (10 tablets/PTP packaging x 3)