Glucanon Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dosage

This medication is taken orally once a day, regardless of meals. It begins with 15 mg once a day as monotherapy, and if insufficiently effective, the dose may be increased to 30 mg once a day. For combination therapy, 15 mg is given once a day. The maximum recommended dose does not exceed 30 mg once a day.

Children's dosage

There is no experience in using this medication in patients under 18 years of age, therefore its use is not recommended.

This medication is used for the treatment of type 2 diabetes and plays a role in improving insulin resistance. It may cause or worsen congestive heart failure in some patients, so careful observation for symptoms of heart failure, weight changes, shortness of breath, and edema should be conducted after starting therapy. Patients with heart failure should not use this medication, and those with heart failure symptoms may need to discontinue or reduce the dosage. Since this medication can cause fluid retention and potentially worsen heart failure, it should be administered with caution in patients with a history of cardiovascular disease, hypertension, or myocardial infarction. This medication should not be given to patients with active bladder cancer or a history of bladder cancer, those with heart failure, liver impairment, severe renal impairment, type 1 diabetes, severe infections or trauma, or pregnant women. When combined with other oral hypoglycemic agents, the risk of hypoglycemia may increase, so caution is warranted, particularly when used with sulfonylureas or insulin. During treatment with this medication, adverse reactions such as edema, weight gain, headache, upper respiratory infections, myalgia, etc., may occur, and symptoms indicating liver dysfunction or visible hematuria and urination issues should be reported to a physician immediately. Women who are pregnant or may become pregnant should consult a specialist as taking this medication may affect the fetus, and those who are breastfeeding should determine its use according to a doctor's guidance. Elderly patients or those with impaired renal function should be closely monitored during treatment with this medication and should receive regular blood sugar and liver function tests. If symptoms such as sudden weight gain, shortness of breath, or edema occur during treatment, immediate medical attention should be sought, and the medication should be taken exactly as prescribed. Finally, this medication is not recommended for use in children as safety and efficacy have not been established.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (excessive and rapid weight changes, shortness of breath, edema), worsening of heart failure, heart and cardiac anomalies, severe edema, heart failure, liver failure, hepatic abnormalities (jaundice), symptoms indicating fatal and non-fatal hepatic failure (fatigue, loss of appetite, discomfort in the right upper abdomen, dark urine, jaundice), hospitalization due to hypoglycemia, serious hypoglycemia, bladder cancer, severe allergic reactions.

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a special container to protect it from light, air, and moisture. The optimal storage temperature is between 15 and 30 degrees Celsius, and extremes of hot or cold should be avoided. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance

White to gray-white, round, and convex tablet

Package unit

30 tablets/bottle, 300 tablets/bottle