Osclo 500mg (Clarithromycin)

Adult dosage

○ Adults The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. ○ Mycobacterial infections Administer 500mg (potency) twice daily. In this case, this medicine should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers Administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as the adult dose. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, patients who are allergic to the ingredients contained in this medication or have had hypersensitivity reactions to specific antibiotics should not be administered this medication. Additionally, patients with cardiac rhythm abnormalities, severe liver impairment, or severe kidney function decline may be at risk if they take this medication. Serious side effects can occur when taken with certain medications, so if you are currently taking any medications, you must consult with a doctor or pharmacist. It is safest for pregnant or breastfeeding women to avoid using this medication. Since this drug is primarily excreted through the liver and kidneys, patients with compromised liver or kidney function may require dosage adjustment. During medication use, allergic reactions, gastrointestinal disturbances, skin rashes, respiratory difficulties, and cardiac symptoms may occur, so if any abnormal symptoms arise, it is essential to inform healthcare professionals immediately. Prolonged or high-dose use may lead to auditory disturbances or tinnitus, so caution is needed. Like other antibiotics, this drug can affect the balance of gut bacteria, so if diarrhea or gastroenteritis symptoms appear, you must stop taking it and consult healthcare professionals. There may be dizziness or confusion when driving or operating machinery, so caution is advised. Regular blood tests and liver and kidney function tests during the course of this medication are important to check for any adverse reactions. In case of overdose, gastrointestinal disturbances or psychiatric symptoms may occur, so you must visit a medical institution immediately for appropriate treatment. To use this medication safely, it is essential to strictly follow the instructions of your doctor or pharmacist and to always pay close attention to interactions with other medications being taken.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, arthralgia, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste abnormalities, anorexia, constipation, stool discoloration, mucosal colitis, hemorrhagic colitis, abdominal pain, frequent diarrhea, fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, hepatic dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, anorexia, jaundice, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, elevated myoglobin in serum and urine, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, sensory disturbances, arthralgia, myalgia, olfactory disturbance, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute pancreatitis, increased amylase, elevated AST and ALT, leukopenia, thrombocytopenia, elevated ALT, elevated AST, elevated γ-GTP, elevated ALP, elevated LDH, elevated serum creatinine, elevated urea, renal failure, nephritis, injection site phlebitis, injection site pain, injection site inflammation, malaise, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, arthralgia, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste abnormalities, anorexia, constipation, stool discoloration, mucosal colitis, hemorrhagic colitis, abdominal pain, frequent diarrhea, fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, hepatic dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, anorexia, jaundice, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, elevated myoglobin in serum and urine, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, sensory disturbances, arthralgia, myalgia, olfactory disturbance, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute pancreatitis, increased amylase, elevated AST and ALT, leukopenia, thrombocytopenia, elevated ALT, elevated AST, elevated γ-GTP, elevated ALP, elevated LDH, elevated serum creatinine, elevated urea, renal failure, nephritis, injection site phlebitis, injection site pain, injection site inflammation, malaise, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it is important to store it at a cool temperature between 15 to 30 degrees Celsius to maintain its effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle