Amadol Tablet

Adult dose

Children over 12 years and adults: The dosage should be adjusted based on the patient’s pain level and therapeutic response. The initial dose of 2 tablets is recommended, with subsequent dosing intervals of at least 6 hours, but not to exceed 8 tablets per day. Administer the lowest effective dose for the shortest duration possible. Avoid administering this medication long-term unless necessary, and if prolonged treatment is required due to the nature and severity of the disease, regular monitoring should be performed to confirm the continuation of this medication. Elderly Administer the standard adult dosage. However, for individuals over 75, the elimination half-life of tramadol is increased by 17%, so it is important to space doses by at least 6 hours. Renal Impaired Patients For moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. In patients with severe renal impairment (creatinine clearance of less than 10 mL/min), this medication is not recommended. Tramadol is very slowly removed during hemodialysis and filtration, so there is no need to re-administer this medication after dialysis for pain relief. Hepatic Impaired Patients For moderate hepatic impairment, it should be considered carefully to extend the dosing interval. For severe hepatic impairment, this medication should not be administered.

Child dose

Children over 12 years and adults: The dosage should be adjusted based on the patient’s pain level and therapeutic response. The initial dose of 2 tablets is recommended, with subsequent dosing intervals of at least 6 hours, but not to exceed 8 tablets per day.

This medication may put stress on the liver, so individuals who regularly consume more than three alcoholic beverages a day should consult a doctor or pharmacist before use. This medication can rarely cause serious skin reactions, so if a rash or allergic symptoms appear, stop taking it immediately and consult a healthcare professional. Exceeding the recommended dosage may increase the risk of seizures, so caution is required, especially when taken with certain antidepressants or narcotic pain relievers. This medication can rarely cause serious allergic reactions; if hypersensitivity or allergic symptoms occur, notify a healthcare professional immediately. It may trigger respiratory distress in patients with severe asthma, so it should only be used in an environment where medical equipment is available. Taking it with alcohol or central nervous system depressants may cause severe drowsiness or respiratory suppression, so avoid combining them or consult a healthcare professional. Patients with head injuries or elevated intracranial pressure may experience worsening conditions when taking this medication, so caution is advised. This medication may lead to psychological and physical dependence, so if used long-term, discuss dependency concerns with a healthcare professional. Patients with impaired liver function or liver disease should consult a doctor before taking this medication and be careful to avoid taking other acetaminophen products simultaneously. Patients with specific genetic metabolic characteristics may experience excessive effects from the active ingredient leading to serious side effects, so it should only be taken after consultation with a healthcare professional. Use in children under 12 years old or adolescents under 18 who have undergone certain surgeries is prohibited, as this age group has a particularly high risk of respiratory suppression. Patients with sleep apnea or hypoxemia may see worsening symptoms after taking this medication, so regular monitoring of their condition is necessary. Elderly individuals or those at risk of hyponatremia should carefully observe for signs of hyponatremia while taking this medication. This medication may interact with certain drugs, increasing the risk of seizures or serious side effects; if taking any other medications, inform a healthcare professional. Pregnant or breastfeeding women should consult a doctor before using this medication as it may affect the fetus or newborn. Caution is necessary when driving or operating machinery, as this medication may cause drowsiness or dizziness. Overdose may result in severe respiratory depression, seizures, liver damage, etc., so strict adherence to the prescribed dosage is required, and if any abnormal symptoms occur, immediate medical attention is needed. Keep this medication out of reach of children to prevent accidental ingestion.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary retention

Mild side effects

• Loss of appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly closed container to prevent air or moisture from entering and kept in a cool place below room temperature (25°C). Storing it this way helps maintain its effectiveness for a longer period.

Appearance

Pale yellow oblong film-coated tablet

Package unit

Domestic use - 30 tablets/bottle, Domestic use - 100 tablets/bottle, Export - 100 tablets/box [10 tablets/PTP*10]