Atorva Tablet 20 mg (Atorvastatin Calcium Trihydrate)

Adult dose

For hyperlipidemia, the recommended starting dose is 10 mg once daily. Patients requiring a more significant reduction in LDL cholesterol can start at 20 mg or 40 mg once daily. The dosing regimen should be individualized within the range of 10-80 mg once daily based on therapeutic goals and patient characteristics, and lipid levels should be analyzed after 2-4 weeks to adjust the dose accordingly. The aim of treatment is to lower LDL cholesterol levels, so it is recommended to monitor LDL cholesterol when initiating treatment and assessing treatment response. If LDL cholesterol levels cannot be monitored, total cholesterol levels can be utilized for monitoring treatment response. For patients with homozygous familial hypercholesterolemia, the dosing regimen is 10-80 mg once daily, administered either alongside other lipid-lowering therapies (e.g., LDL apheresis) or when these therapies are not possible.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17), the recommended starting dose is 10 mg once daily, and the maximum recommended dose is 20 mg once daily. The administered dose should be adjusted according to the therapeutic goals.

This medication may cause muscle-related symptoms, and patients should immediately inform their doctor if they experience muscle pain, weakness, or cramps. If there is a significant increase in creatine kinase (CK) levels in blood tests, this medication should be discontinued. It should not be used in patients with active liver disease or severely impaired liver function, in those with muscle disorders, during pregnancy or in women who might become pregnant, and in children under the age of 10. Caution is advised for patients with a history of alcohol abuse or liver disease, impaired kidney function, hypothyroidism, elderly patients, who should undergo regular blood tests. This medication can affect liver function; if symptoms of hepatitis or jaundice, nausea, vomiting, or fatigue occur, medical attention should be sought immediately. Furthermore, it should not be used in pregnant or nursing women, and fertile women should use appropriate contraception while taking this medication. This medication may interact with other drugs; therefore, it's essential to inform the doctor or pharmacist of any medications currently being taken. Special caution is required when taken with certain antibiotics, antifungals, antivirals, immunosuppressants, and some blood pressure medications. In case of overdose, there are no specific antidotes, so treatment should be symptomatic and liver function and muscle status must be closely monitored. Lastly, keep this medication out of the reach of children and store it in its original container to prevent deterioration or misuse.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory difficulties, yellowing of the skin or eyes (jaundice), profound lethargy, liver dysfunction (jaundice), sudden and severe headaches, thunderclap headache, leg pain

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication is sensitive to air and moisture; therefore, it must be stored in a tightly closed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage will help preserve the effectiveness of the medication for a longer period.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle