Tranopen Semi Tablet

Adult dose

For children aged 12 and older and adults: The dosage is adjusted based on the patient's level of pain and treatment response. The initial dose of 4 tablets is recommended, and subsequent doses should be spaced at least 6 hours apart, not exceeding 16 tablets per day. The minimum effective dose should be administered for the shortest period possible. This medication should not be taken for longer than necessary, and if long-term treatment is required due to the nature and severity of the condition, regular monitoring should be conducted to confirm the necessity of continued administration of this medication. Elderly Administer the usual adult dosage. However, in elderly patients over 75 years of age, when tramadol is taken orally, the elimination half-life of tramadol increases by 17%, thus the medication should be administered at intervals of at least 6 hours. Patients with renal impairment In patients with moderate renal impairment (creatinine clearance 10-30 ml/min), the dosing interval should be extended to 12 hours. In patients with severe renal impairment (creatinine clearance less than 10 ml/min), administration of this medication is not recommended. Tramadol is very slowly removed during hemodialysis and filtration, so there is no need to re-administer this medication post-dialysis to maintain analgesic effects. Patients with hepatic impairment In patients with moderate hepatic impairment, careful consideration should be given to extending the dosing interval. This medication should not be administered to patients with severe hepatic impairment.

Child dose

For children aged 12 and older and adults: The dosage is adjusted based on the patient's level of pain and treatment response. The initial dose of 4 tablets is recommended, and subsequent doses should be spaced at least 6 hours apart with a maximum of 16 tablets per day.

This medication may burden the liver, so individuals who regularly consume more than three glasses of alcohol daily should consult a doctor or pharmacist before use. If any unusual reactions, such as rashes or itching, occur during treatment, discontinue use immediately and consult a physician. Individuals at risk of seizures should use caution when taking this medication, as the risk of seizures may increase when taken with certain antidepressants or other medications. Patients with severe respiratory conditions should use this medication under medical supervision as it may cause difficulty in breathing. This medication may cause severe drowsiness, respiratory depression, or comatose states when taken with central nervous system depressants or alcohol, so caution is needed. Patients with head injuries or brain diseases should be careful as symptoms may worsen with this medication. This medication has the potential to cause dependency and addiction; therefore, strict adherence to a doctor's instructions is necessary for long-term use. Patients with weakened liver function should consult a physician before taking this medication and should take care not to exceed the recommended dosage. Children, especially those under 12 or adolescents under 18 who have had tonsillectomies, should not use this medication. Pregnant or nursing women must consult a physician before using this medication and are advised to avoid use during breastfeeding. Care is advised when driving or operating machinery as this medication may cause drowsiness or dizziness. Overdose of this medication poses serious risks such as severe respiratory depression, seizures, and liver damage, so the prescribed dosage must be strictly adhered to. Caution should be exercised to avoid concurrent use with other analgesics or acetaminophen-containing medications, as drug interactions may occur; patients should inform their healthcare providers of all medications being taken. Report any adverse reactions immediately to healthcare providers during treatment, as regular monitoring may be required.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied by respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air from entering and kept in a cool place below room temperature (25 degrees Celsius). This will help maintain the effectiveness of the medication and prevent deterioration.

Appearance

Light yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle