Minirin Melt Sublingual Tablets 120 Micrograms (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer 60㎍ of desmopressin sublingually at bedtime. If the effect is insufficient after one week, increase the dose to 120㎍; if the effect remains insufficient, increase the dose at one-week intervals up to 240㎍. Fluid intake should be restricted during treatment. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Initiating treatment with this medicine is not recommended in patients aged 65 years or older. If treatment is necessary in elderly patients, monitor serum sodium levels and other parameters closely (see 5. General Precautions in Precautions for Use).

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 120㎍ of desmopressin sublingually at bedtime. If the effect is insufficient, the dose may be increased to 240㎍. Fluid intake should be restricted during treatment. If signs of fluid retention or hyponatremia (headache, nausea/vomiting, weight gain, and, in severe cases, convulsions) occur, discontinue treatment until the patient has fully recovered. If treatment with this medicine is to be restarted, fluid intake must be strictly restricted. Whether to continue treatment should be determined after 3 months of administration, with treatment withheld for at least 1 week.

This medication helps regulate the body's fluid balance. Caution must be taken to avoid excessive fluid intake while using this medication. Excessive fluid intake can lower blood sodium levels, potentially leading to hyponatremia or water intoxication, which may result in coma. Particularly, elderly patients, those with impaired kidney function, and patients with certain heart conditions should exercise greater caution when using this medication, and it is important to limit fluid intake. Patients with allergic reactions to this medication or severely impaired kidney function, as well as those on diuretics, should avoid using it. Pregnant or breastfeeding women should carefully consider the effects on the fetus or newborn when using this medication, and especially in the case of breastfeeding, it is advisable to discontinue breastfeeding. While taking this medication, regular monitoring of blood sodium levels and weight changes should be performed to observe for any abnormal signs. Additionally, this medication may interact with certain other medications, so if you are taking any other medications, you must inform your healthcare provider. In the case of overdose, symptoms such as headache, nausea, seizures, or loss of consciousness may occur, so you should consult a healthcare professional immediately, and if necessary, receive appropriate measures such as diuretics. This medication does not affect driving or operating machinery, but caution should be exercised if adverse reactions occur.

• coma
• seizures
• weight gain
• hyponatremia
• emotional disturbances
• headache
• abdominal pain
• nausea
• allergic skin reactions
• dizziness

Store this medication in a tightly closed container to protect it from air and light. It is also safe to store at room temperature, away from extreme hot or cold conditions.

Appearance

White round tablet

Package unit

10 tablets/PTPX3/box