Minirin Melt Sublingual Tablet 60 Micrograms (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) : Administer 60㎍ of desmopressin sublingually at bedtime. If the effect is insufficient after one week, increase the dose to 120㎍; if the effect remains insufficient, increase the dose at one-week intervals up to 240㎍. Fluid intake should be restricted during treatment. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Initiating treatment with this medicine is not recommended in patients aged 65 years or older. If treatment is necessary in elderly patients, monitor serum sodium levels and other parameters closely (see 5. General Precautions in Precautions for Use).

Child dose

Primary nocturnal enuresis (age 5 years and older) : Administer 120㎍ of desmopressin sublingually at bedtime. If the effect is insufficient, the dose may be increased to 240㎍. Fluid intake should be restricted during treatment. If signs of fluid retention or hyponatremia (headache, nausea/vomiting, weight gain, and, in severe cases, convulsions) occur, discontinue treatment until the patient has fully recovered. If treatment with this medicine is to be restarted, fluid intake must be strictly restricted. Whether to continue treatment should be determined after 3 months of administration, with treatment withheld for at least 1 week.

This medication helps to regulate the body's fluid balance. When taking this medicine, fluid intake should be restricted to the point of feeling thirsty. Excessive fluid intake may lower sodium levels in the body and cause serious side effects such as coma. This medication should not be used in patients with a history of allergic reactions, certain kidney diseases, heart failure, or those taking diuretics. Individuals with hypertension, cardiovascular diseases, or kidney diseases should use it with caution. Women who are pregnant or may become pregnant, children, and the elderly should also use this medication carefully, especially in the presence of conditions that could cause fluid and electrolyte imbalances. During use, side effects such as headache, dizziness, nausea, weight gain, and skin allergic reactions may occur, and if any unusual symptoms arise, immediate consultation with a healthcare provider is advised. Additionally, this medication may interact with other drugs, so it is essential to inform healthcare providers, especially when taking antidepressants, diuretics, corticosteroids, or nonsteroidal anti-inflammatory drugs. Caution is necessary during pregnancy as it may induce uterine contractions, and it is recommended to discontinue breastfeeding during this time due to the potential excretion of the drug into breast milk. In case of overdose, serious symptoms such as headaches, nausea, seizures, or loss of consciousness may occur, requiring immediate medical attention for proper treatment. Using this medication does not significantly affect driving or machine operation, but caution may still be needed depending on individual physical condition.

• unconsciousness
• convulsions
• weight gain
• hyponatremia
• emotional disturbances
• headache
• abdominal pain
• nausea
• allergic skin reactions
• dizziness

This medication may be sensitive to air or humidity, so it should be stored in a sealed container. Furthermore, it is best to store the medication at a moderate room temperature, avoiding excessively hot or cold areas.

Appearance

White round tablet

Package unit

10 tablets/PTPX3/box