Prokalin Tablets 50 mg (Bicalutamide)

Adult dose

1. Adults and elderly men receiving this medicine in combination with a luteinizing hormone-releasing hormone (LHRH) analog or surgical castration : Administer 50 mg of bicalutamide orally once daily. Start taking this medicine at least 3 days before administration of the luteinizing hormone-releasing hormone (LHRH) analog or at the same time as surgical castration. 2. Monotherapy in patients with locally advanced, nonmetastatic prostate cancer at high risk of disease progression, or adjuvant therapy to radical prostatectomy or radiation therapy : Adult and elderly men: Administer 150 mg of bicalutamide orally once daily. Continue this 150 mg regimen for at least 2 years or until the disease progresses.

This drug should not be used in women and children under 18 years of age. Do not take this medication if you have an allergic reaction to this drug or its components. This drug should not be administered to patients taking specific medications such as terfenadine, astemizole, and cisapride. Patients with a history of liver damage or severe liver impairment may be at risk when using this medication, hence caution is necessary. This drug contains lactose, therefore patients with lactose intolerance or related genetic disorders should avoid taking it. Patients with liver function issues should be cautious as this drug is primarily metabolized in the liver, posing a risk of accumulation in the body. While taking this drug, side effects such as dizziness, facial flushing, dyspepsia, skin rash, hematuria, and gynecomastia may occur, so consult medical personnel immediately if unusual symptoms arise. Rarely, serious side effects such as heart issues, liver function deterioration, and hypersensitivity reactions may occur, requiring regular check-ups and monitoring. This medication may cause changes in liver function; therefore, it is important to have regular liver function tests. This medication can inhibit specific enzymes in the liver, posing a risk of interaction with other medications, so be sure to inform your doctor about any other drugs you are taking. Caution is required when driving or operating machinery as confusion or drowsiness may occur. Since this drug contains lactose, patients with lactose hypersensitivity should consult a physician before use. Patients with diabetes or issues with blood glucose control should regularly check their blood sugar levels while on this medication. Patients with arrhythmias or prolonged QT intervals should be evaluated for heart condition before taking this drug. This drug is contraindicated for women; pregnant or nursing women should never take it. In case of overdose, there is no specific antidote, so appropriate treatment should be given according to symptoms, and blood dialysis may not be effective. Keep this medication out of reach of children and store it securely in its original container. This medication may affect male reproductive function, so it is recommended to use appropriate contraception methods for a certain period after taking it. Elderly patients may experience adverse reactions related to the heart and circulatory system more frequently, so their condition should be monitored closely during treatment.

• Anemia
• dizziness
• facial flushing
• abdominal pain
• constipation
• nausea
• diarrhea
• rash
• hematuria
• gynecomastia

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help preserve the effectiveness of the drug and ensure its safe use.

Appearance

White round film-coated tablets

Package unit

28 tablets (14 tablets/PTP x 2)