Bicalud Tablets (Bicalutamide)

Adult dose

1. Adults and elderly men receiving this medicine in combination with a luteinizing hormone-releasing hormone (LHRH) analog or surgical castration : Administer 50 mg of bicalutamide orally once daily. Start taking this medicine at least 3 days before administration of the luteinizing hormone-releasing hormone (LHRH) analog or at the same time as surgical castration. 2. Monotherapy in patients with locally advanced, nonmetastatic prostate cancer at high risk of disease progression, or adjuvant therapy to radical prostatectomy or radiation therapy : Adult and elderly men: Administer 150 mg of bicalutamide orally once daily. Continue this 150 mg regimen for at least 2 years or until the disease progresses.

This medication should not be used by women or children under 18 years of age. Patients who are allergic to this drug or any of its components should not be administered this medication. It is also contraindicated in patients taking specific drugs such as terfenadine, astemizole, or cisapride. Patients with a history of liver damage or severe liver dysfunction should not take this drug. Additionally, this medication contains lactose, so patients with lactose intolerance or related genetic disorders should avoid it. Patients with impaired liver function may have a slower metabolism of this drug, increasing the risk of drug accumulation, so it should be used cautiously. Various side effects may occur while taking this medication, with common ones including anemia, dizziness, facial flushing, indigestion, rash, hematuria, gynecomastia, and weakness. Rarely, serious side effects such as liver dysfunction, liver failure, heart problems, and lung diseases may occur, so it is essential to consult a healthcare professional immediately if any abnormal symptoms appear. Regular monitoring of liver function is important, and if severe liver damage is suspected, the medication should be discontinued immediately. This drug is mainly metabolized in the liver and may inhibit enzymes involved in liver metabolism, so caution is required regarding interactions with other medications, especially specific heart medications, immunosuppressants, and antibiotics. Always inform your healthcare provider about any concomitant medications. This drug does not affect driving or machine operation abilities; however, caution is needed as drowsiness or confusion may occur. This medication is prohibited for use by women, and pregnant or nursing women should not take it. It should not be administered to children under 18 years. In elderly patients, cardiac and circulatory function may be impaired, so careful administration should be considered due to the potential for side effects. In case of overdose, there is no specific antidote, so appropriate treatment should be administered based on symptoms, and dialysis may not be effective. This medication should be kept out of reach of children and stored in its original container for safety.

• Anemia
• dizziness
• facial flushing
• abdominal pain
• constipation
• nausea
• diarrhea
• rash
• hematuria
• gynecomastia

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius to help preserve the drug's efficacy and safety.

Appearance

White round film-coated tablet

Package unit

28 tablets (14 tablets/PTP*2)