Rabeone Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: The usual dose is 10 mg taken orally once daily, with the possibility to take 20 mg once daily depending on symptoms. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not treated after 8 weeks, an additional 8 weeks of 10 mg or 20 mg can be taken orally twice daily. However, 20 mg twice daily is only for patients with severe mucosal damage confirmed. For symptom relief of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is needed. After symptoms resolve, on-demand therapy with 10 mg once daily can be used to manage any subsequent symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily depending on the patient condition. For Helicobacter pylori eradication: Infected patients should undergo eradication therapy. It is recommended to administer this medication 20 mg, clarithromycin 500 mg, and amoxicillin 1 g twice daily for 7 days in combination. For Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dosage may be adjusted up to 120 mg daily based on individual patient needs. Up to 100 mg can be given as a single daily dose; the 120 mg dose is divided into two doses of 60 mg daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to 1 year. For patients with liver dysfunction, care should be taken when administering this medication due to the risk of hepatic encephalopathy being reported in patients with liver cirrhosis. For children, safety has not been established. For the elderly, careful administration is necessary as liver function is often impaired.

Child dose

Safety has not been established for children.

This medication should not be used in patients with specific allergic reactions or those who have had allergies to this medication or similar components in the past. Additionally, it is prohibited for patients currently taking certain antibiotics or other medications, as well as for pregnant or breastfeeding women. Patients with liver function problems or elderly patients, and those with a history of drug allergies need to take caution when using this medication. If allergic symptoms such as skin rash or itching occur during the use of this medication, it should be discontinued immediately. Regular blood tests and liver function tests are required, and appropriate actions should be taken if abnormal findings are detected. Side effects may occur in various body parts such as the heart, gastrointestinal system, nervous system, respiratory system, and skin, so if symptoms appear, consult with healthcare professionals. Long-term use may increase the risk of fractures due to osteoporosis, so regular evaluations are necessary. Since this medication suppresses gastric acid secretion, there may be a slight increase in the risk of gastrointestinal bacterial infections, so if symptoms such as diarrhea persist, visit a hospital. Caution is required as drowsiness may occur while driving or operating machinery. There may be interactions with other medications, so it is essential to inform healthcare professionals about any other medications being taken. It is safer not to use this medication during pregnancy or breastfeeding. Safety has not been established for children, so it is recommended not to use it.

Serious side effects

Hives, chest tightness, jaundice, acute interstitial nephritis, fulminant hepatitis, liver dysfunction, severe allergic reactions, toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome (severe mucocutaneous reactions), severe skin reactions, dyspnea, asthma attacks, pulmonary embolism, ventricular tachycardia, thrombophlebitis, severe edema, hypomagnesemia, severe neurological symptoms (severe headache, thunderclap headache, seizures, confusion, visual disturbances

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellowish round enteric-coated tablet

Package unit

28 tablets (7 tablets/PTPX4)