Itranaconazole 200 mg Tablet

Adult dosage

(Tablets)(Capsules) Administration immediately after a meal is preferred. Vulvovaginal candidiasis: Administer itraconazole 200 mg twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. Pityriasis versicolor: Administer 200 mg once daily for 7 days. Tinea corporis, tinea cruris (jock itch): Administer 100 mg once daily for 15 days. Tinea manuum (interdigital type), tinea pedis (interdigital type): Administer 100 mg once daily for 15 days. Tinea manuum (palms), tinea pedis (soles): Administer 100 mg once daily for 30 days, or 200 mg twice daily for 7 days. Oral candidiasis: Administer 100 mg once daily for 15 days. Fungal keratitis: Administer 200 mg once daily for 21 days. Onychomycosis, pulse therapy: Administer 200 mg twice daily for 1 week, followed by a 3-week drug-free period; this constitutes 1 cycle. Administer up to 2 cycles if only the fingernails are infected, and up to 3 cycles if the toenails are infected. Onychomycosis, continuous therapy: Administer 200 mg once daily for 3 months. Systemic fungal infections: In patients with impaired immune function, double the dose if necessary. Aspergillosis: 200mg once daily for 2～5 months. For invasive or disseminated disease, increase the dose to 200mg twice daily. Candidiasis: 100～200mg once daily for 3 weeks～7 months. Cryptococcal meningitis: 200mg twice daily for 2 months～1 year. Maintenance therapy: 200mg once daily. Paracoccidioidomycosis: 100mg once daily for 6 months. (Oral solution) Do not take with food. Hold this medicine in the mouth for approximately 20 seconds to allow it to contact the entire oral cavity, then swallow. After swallowing, do not rinse the mouth so that the medicine remains in the mouth for as long as possible. Oral and esophageal candidiasis: Take 200 mg (20 mL) daily in 1～2 divided doses for 1 week. If there is no effect after 1 week, continue treatment for another week. Fluconazole-resistant oral and esophageal candidiasis: Take 200～400 mg (20～40 mL) daily in 1～2 divided doses for 2 weeks. If there is no effect after 2 weeks, continue treatment for another 2 weeks. Even if symptoms do not improve, do not use 400 mg daily for more than 14 days.

Children's dosage

Prevention of fungal infections: Administer 5 mg/kg of body weight daily in 2 divided doses.

It is crucial not to use this medication in patients with impaired heart function. Patients with congestive heart failure or a history of heart failure should not be treated with this medication, and treatment should be stopped immediately if symptoms of heart failure appear. Patients who have had hypersensitivity reactions to this medication or those who may experience serious side effects when used with certain drugs should identify and avoid contraindicated medications. Pregnant or potentially pregnant women and nursing mothers should not use this medication. In patients with decreased liver function, metabolism may be slowed, and regular liver function tests should be conducted while carefully administering this medication. Patients with reduced kidney function may also require dosage adjustments. This medication can induce various adverse reactions, with headache, nausea, abdominal pain being commonly reported, and less frequently serious side effects such as hepatotoxicity, heart issues, and allergic reactions may occur. If abnormal symptoms arise, consulting a physician immediately is essential. Due to numerous drug interactions, it is important to inform doctors or pharmacists of any other medications being taken, especially when using antacids that reduce stomach acid or calcium channel blockers. Pregnant or nursing women should avoid using this medication, and women of childbearing potential should ensure proper contraception during and for a specified time after treatment. The safety of this medication has not been fully established for children and the elderly; therefore, it should only be used cautiously when necessary, with careful monitoring and dosage adjustments. In the case of overdose, there is no specific antidote, so it is important to receive appropriate treatment according to symptoms, and this medication is not removed by hemodialysis. Store this medication in a place out of reach of children, and do not remove it from its original container and store it in another container.

Headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory tract infection, leukopenia, hypersensitivity, taste disorder, sensory impairment, paresthesia, tinnitus, constipation, diarrhea, indigestion, bloating, vomiting, abnormal liver function, hyperbilirubinemia, itching, rash, urticaria, polyuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusional state, peripheral neuropathy, dizziness, drowsiness, tremor, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, voice disorder, cough, gastrointestinal disorder, hepatic failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, renal impairment, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, angioedema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, transient hearing loss, permanent hearing loss, ventricular extrasystoles, atrioventricular block, palpitations, increased bowel motility, belching, glossitis, stomatitis, abdominal pain in the lower back, pancreatitis, increased serum total protein, increased total bilirubin, increased LAP, loss of appetite, malaise, brown urine, increased liver enzyme levels, Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell's syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocyte destructing vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive proteinuria, positive glucosuria, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, increased serum triglycerides, burning sensation, increased serum uric acid, increased serum potassium, serum sickness, angioedema, anaphylactic reaction, hypertriglyceridemia, tremor, blurred vision, congestive heart failure, dyspnea, significant hepatotoxicity, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, erythema multiforme, exfoliative dermatitis, leukocyte destructing vasculitis, hair loss, photosensitivity, increased serum creatine phosphokinase levels

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is essential to maintain storage temperatures between 1°C and 30°C to preserve the medication's effectiveness and safety.

Appearance

White or pale yellow oblong tablet

Package unit

30 tablets/bottle, 100 tablets/bottle