Medication info
Rabeprazole Sodium 20 mg (Rabeprazole Sodium)

Rabeprazole Sodium 20 mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›20mg / 1 tablet
Manufacturer / importer
제이더블유중외제약(주)
Appearance
Pale yellow, round enteric-coated tablets
Packaging
28 tablets (7 tablets/Alu-Alu X 4)
Approval status
Active

MFDS item code 200701491 · Notified 2007.02.02 · Insurance code 644900670

Summary

Main use
Relief of symptoms of gastric ulcers, duodenal ulcers, and gastroesophageal reflux disease, and treatment of Helicobacter pylori infection
Who takes it
Adults · Children
Adult dose
For gastric ulcers and duodenal ulcers: Typically, adults are given 10 mg of rabeprazole sodium orally once daily. Depending on symptoms, 20 mg can be taken orally once daily. For gastric ulcers, it is administered for up to 8 weeks, and for duodenal ulcers, up to 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg is administered orally once daily for 4-8 weeks. If symptoms persist after an 8-week treatment, further evaluation is needed.
Child dose
Safety in pediatric patients has not been established.

Ingredients

Manufacturer
제이더블유중외제약(주)

Efficacy & effects

Relief of symptoms of gastric ulcers, duodenal ulcers, and gastroesophageal reflux disease, and treatment of Helicobacter pylori infection

  • Gastric ulcers
  • duodenal ulcers
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • symptoms of gastroesophageal reflux disease
  • gastrointestinal ulcers
  • Zollinger-Ellison syndrome
View approved original text

This medication is used to treat gastric ulcers and duodenal ulcers and is effective in alleviating symptoms of erosive or ulcerative gastroesophageal reflux disease. It can also be applied to long-term maintenance therapy for gastroesophageal reflux disease. It is used in combination with antibiotics for the treatment of gastrointestinal ulcers in patients with Helicobacter pylori infection, and it helps with Zollinger-Ellison syndrome. This medication aids in improving gastrointestinal-related diseases.

How to take

Adult dose

For gastric ulcers and duodenal ulcers: Typically, adults are given 10 mg of rabeprazole sodium orally once daily. Depending on symptoms, 20 mg can be taken orally once daily. For gastric ulcers, it is administered for up to 8 weeks, and for duodenal ulcers, up to 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg is administered orally once daily for 4-8 weeks. If symptoms persist after an 8-week treatment, further evaluation is needed.

Child dose

Safety in pediatric patients has not been established.

Precautions

This medication should not be used in patients with allergies to specific components or a history of hypersensitivity. Also, caution is needed as there may be allergic reactions when used with certain antibiotics. Pregnant or nursing women are advised not to take this medication as it may affect the fetus or infant. Patients with poor liver function or the elderly should use this medication cautiously as adverse reactions may occur. If allergic symptoms such as skin rash or itching occur while taking this medication, discontinue immediately. Regular blood tests or liver function tests should be performed, and if abnormalities are found, discontinue use and consult a doctor. Various side effects may occur in multiple body systems including the heart, gastrointestinal, nervous, respiratory, skin, eyes, and urinary system, so it is important to report any unusual symptoms immediately. Long-term use of this medication may increase the risk of fractures, so proper management is required. This medication can interact with other medications, so if you are taking other drugs, be sure to inform your healthcare provider. Caution is required when driving or operating machinery as drowsiness may occur. In case of overdose, there is no specific antidote, so necessary treatment according to the symptoms should be received, and tablets should not be chewed or crushed but swallowed whole. Keep out of reach of children and do not transfer to other containers.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, fulminant hepatitis, liver dysfunction, jaundice, acute interstitial nephritis, pulmonary embolism, ventricular tachycardia, thrombophlebitis, ventricular fibrillation, toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome, interstitial pneumonia, sudden death, coma, anaphylaxis, angioedema, hypomagnesemia, decrease in platelets, decrease in neutrophils, decrease in white blood cells

Mild side effects

  • Rash
  • urticaria
  • itching
  • decrease in red blood cells
  • decrease in white blood cells
  • increase in white blood cells
  • increase in eosinophils
  • increase in neutrophils
  • decrease in lymphocytes
  • anemia
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  • petechiae
  • lymphadenopathy
  • hypochromic anemia
  • pancytopenia
  • agranulocytosis
  • decrease in platelets
  • hemolytic anemia
  • increase in ALT
  • increase in AST
  • increase in ALP
  • increase in γ-GTP
  • increase in LDH
  • hypertension
  • myocardial infarction
  • abnormal electrocardiogram results
  • migraine
  • syncope
  • angina
  • heart block
  • palpitations
  • bradycardia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and kept at room temperature between 1 degree to 30 degrees Celsius. Proper storage maintains the effectiveness of the medication and allows for safe use.

Appearance and packaging

Appearance

Pale yellow, round enteric-coated tablets

Package unit

28 tablets (7 tablets/Alu-Alu X 4)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.