Plavix 75 mg (Clopidogrel Sulfate)

Adult dose

For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer 75 mg of clopidogrel orally once a day. For patients with acute coronary syndrome (unstable angina or non-ST elevation myocardial infarction), start with a loading dose of 300 mg on the first day of treatment and continue with a maintenance dose of 75 mg orally once a day thereafter. At this time, aspirin 75-325 mg should be administered once a day alongside this medication.

This medication is a drug that inhibits platelet aggregation in the blood to prevent thrombus formation. In patients with a genetic deficiency of the CYP2C19 enzyme, the effectiveness of this drug may be reduced, in which case alternative treatment options should be considered. Taking this drug with medications that activate the CYP2C19 enzyme may increase the concentration of the active ingredient of this drug and raise the risk of bleeding, so co-administration should be avoided. Patients with allergies to this medication or those with bleeding, severe liver impairment, nursing women, and those with genetic lactose intolerance should not take this medication. Patients at high risk of bleeding or with bleeding disorders, severe liver or kidney dysfunction, acute stroke patients, hypertensive patients, elderly, and underweight patients should take this medication with caution, and it should be discontinued 5-7 days before any scheduled surgery. This medication can cause bleeding; therefore, if any bleeding symptoms occur, consult a physician immediately, especially when combined with other drugs that increase the risk of bleeding. During treatment with this drug, it is important to regularly monitor for bleeding and hematological abnormalities through blood tests and other examinations. This medication may cause various side effects such as gastrointestinal disturbances, diarrhea, rash, headache, and dizziness, and in serious cases, hematologic disorders such as thrombocytopenia or acquired hemophilia can occur. Women who are pregnant or breastfeeding should consult a physician before taking this drug, as the risk of bleeding may increase during pregnancy, warranting caution. This medication may interact with other medications, particularly those associated with bleeding risk, anticoagulants, non-steroidal anti-inflammatory drugs, selective serotonin reuptake inhibitors (SSRIs), and should be discussed with a doctor when used in combination. Overdose may increase the risk of bleeding, and there are no specific antidotes, so if bleeding symptoms occur, you should visit a medical facility immediately. This medication should be kept out of the reach of children, and care must be taken not to store it in different containers, as this could jeopardize its quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, shortness of breath, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme tiredness, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, etc.

Mild side effects

• Headache
• dizziness
• abdominal pain
• dyspepsia
• diarrhea
• nausea
• fatigue
• rash
• itching
• joint pain

This medication may be sensitive to air or moisture and should be stored in a tightly sealed container. It is recommended to maintain storage temperatures between 1 and 30 degrees Celsius to preserve the effectiveness of the drug.

Appearance

Pink round film-coated tablet

Package unit

30 tablets (10 tablets/blister x 3), 100 tablets/bottle