Pharmacephacler Sustained Release Tablet 375 mg (Cefaclor Hydrate)

Adult dose

As cefaclor hydrate, take 375 mg (potency) orally twice daily. The tablet should be swallowed whole and should not be crushed, broken, or chewed. This medication can be taken orally regardless of meals.

This medication should not be used in patients who have experienced severe allergic reactions or shock from this medication or cephalosporin antibiotics in the past. Patients allergic to penicillin antibiotics, those with allergic tendencies, severe kidney diseases, those who have difficulty with oral intake, the elderly, and patients in poor systemic condition should use this medication with caution. During treatment, symptoms such as shock, severe allergic symptoms, skin rash, blood abnormalities, liver or kidney function abnormalities, gastrointestinal disorders, respiratory issues, and central nervous system symptoms may occur, and if any symptoms develop, immediate consultation with a physician is necessary. To prevent the occurrence of resistant bacteria, it is advisable to conduct sensitivity testing and use this medication only for the minimum necessary duration. There may be interactions with other medicines, particularly when taken together with probenecid, antacids, drugs affecting the kidneys, anticoagulants, oral contraceptives, among others. The safety of this medication in pregnant or breastfeeding women has not been sufficiently confirmed, so it should be used cautiously only if absolutely necessary. Dosage and administration for children or the elderly should be adjusted, monitoring their condition closely. In cases of overdose, symptoms such as nausea, vomiting, and abdominal discomfort may occur, and immediate medical attention should be sought for appropriate treatment. This medication works by interfering with bacterial cell wall synthesis to kill bacteria.

Serious side effects

Shock, anaphylactic symptoms (generalized flushing, swelling, difficulty breathing, angioedema, sensory disturbances, syncope, hypertension, vascular dilation), urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis, liver abnormalities (including jaundice), acute renal failure, severe edema, severe colitis, interstitial pneumonia, eosinophilic lung infiltrates, severe neurological symptoms (including seizures), severe allergic reactions

Mild side effects

• Rash
• itching
• fever
• lymphadenopathy
• joint pain
• serum sickness-like reactions
• agranulocytosis
• neutropenia
• pancytopenia
• anemia

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best stored at room temperature, between 1 and 30 degrees Celsius. This helps maintain the effectiveness of the medication for a longer time.

Appearance

Blue rectangular sustained release tablet

Package unit

30 tablets/bottle, 200 tablets/bottle