Biclar Sustained Release Tablet 375 mg (Cefaclor Hydrate)

Adult dose

Administer 375 mg (potency) of Cefaclor orally twice a day. For infections caused by Streptococcus pyogenes (Group A beta-hemolytic), it should be administered for more than 10 days. The tablet should be taken whole, without crushing, breaking, or chewing. It can be taken orally without regard to meals.

This medication is an antibiotic that kills bacteria by interfering with the synthesis of bacterial cell walls by binding to specific proteins. Before using this medication, you must inform your doctor if you have a history of severe allergic reactions or shock to this medication or similar antibiotics. Use with caution if you are allergic to penicillin antibiotics or have a tendency to have allergic symptoms such as asthma or skin rashes. Patients with severely impaired kidney function, elderly patients, or patients in poor nutritional status should be closely monitored when taking this medication due to the risk of bleeding caused by vitamin K deficiency. Patients with gastrointestinal diseases, especially those with a history of colitis, should consult a doctor immediately if symptoms such as abdominal pain or diarrhea occur during treatment with this medication. Rarely, this medication may cause serious side effects such as respiratory distress, generalized rash, hives, rashes, severe skin reactions, blood disorders, liver or kidney function abnormalities; if any unusual symptoms occur, stop the medication immediately and seek medical attention. There may be interactions with other medications, so you should inform your doctor of any drugs you are currently taking, especially when using drugs that affect the kidneys, anticoagulants, antacids, or oral contraceptives. Pregnant or nursing women should carefully decide on the use of this medication after consulting a doctor, as its safety has not been fully established. Caution is necessary when using this medication in children as its effects and safety have not been established. Elderly patients may experience side effects more easily due to decreased bodily functions, so dosage and dosing intervals should be adjusted while being closely monitored. This medication may affect urine test results, so be sure to inform the medical staff during testing. In case of overdose, symptoms such as nausea, vomiting, abdominal discomfort, and diarrhea may occur; seek appropriate treatment at a hospital immediately. To prevent the emergence of resistant bacteria, use this medication only for the minimum duration necessary based on sensitivity testing, and consult medical staff immediately if any allergic symptoms or adverse reactions occur during treatment.

Serious side effects

• Shock
• hives
• edema
• respiratory distress
• vascular edema
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• jaundice
• hepatitis
• acute renal failure

Mild side effects

• Generalized rash
• vascular edema
• sensory disturbances
• syncope
• hypertension
• vasodilation
• rash
• itching
• fever
• lymphadenopathy

Store this medication in a tightly closed container to prevent air from entering, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a long time.

Appearance

Blue rectangular sustained release tablet

Package unit

30 tablets/bottle, 100 tablets/bottle