Herpam 750 mg (Famciclovir)

Adult dosage

1. Treatment of herpes zoster Adults: Administer 750 mg of famciclovir orally once daily for 7 days. Take it at the same time every day. It is advisable to start treatment as soon as symptoms appear after infection. 2. Patients with renal impairment: In patients with renal impairment, use caution when adjusting the dose because creatinine clearance of this drug is reduced. The dosage for these patients is as follows. 1) Treatment of herpes zoster Creatinine clearance (mL/min/1.73㎡) 30～59: 250 mg per dose, twice daily Creatinine clearance (mL/min/1.73㎡) 10～29: 250 mg per dose, once daily 2) If only serum creatinine is known, creatinine clearance may be calculated using the following formula. Men: {body weight (kg) × (140-age)}/ {72 × serum creatinine (mg/dL)} Women: 0.85 × the value calculated for men 3) Patients with renal impairment undergoing hemodialysis: For patients on hemodialysis, administration every 48 hours is advisable, taking the dialysis interval into consideration. Four hours of hemodialysis reduces the plasma concentration of this drug by approximately 75%; therefore, administer the entire dose immediately after dialysis. 3. Patients with hepatic impairment: No dose adjustment is necessary for patients with chronic compensated liver disease. There is insufficient treatment experience in patients with overt chronic decompensated liver disease; therefore, no clear recommended dose has been established.

This medication should not be used in patients allergic to this drug or its components. Additionally, because it contains lactose, it should not be administered to patients with lactose intolerance or specific genetic metabolic disorders. Caution is necessary for patients with impaired kidney function when using this medication. During treatment, side effects such as headache, dizziness, nausea, vomiting, and skin rash may occur, and if symptoms are severe, consultation with a healthcare professional is advised. This medication does not cure genital herpes, so it is essential to avoid sexual contact when symptoms are present and maintain safe sex practices. If symptoms such as dizziness or drowsiness occur, it is advisable to refrain from driving or operating machinery. In patients with severe liver dysfunction, the effectiveness may be reduced, so caution is warranted. There may be interactions when taken with other medications, so it is crucial to inform the healthcare provider of any other medications being taken. Pregnant or breastfeeding women should consult a doctor before taking this medication, and women who may become pregnant should use it cautiously. The safety and efficacy of this medication have not been fully established in children under 18 years of age, so it is preferable not to use it in this age group. Elderly patients may require dosage adjustment based on kidney function. In case of overdose, appropriate treatment is necessary, and the drug concentration can be reduced through dialysis. This medication should be stored in a dry place below 30 degrees Celsius and kept out of reach of children, and it is advisable not to transfer it to another container.

• headache
• nausea
• thrombocytopenia
• leukopenia
• neutropenia
• dizziness
• confusion
• drowsiness
• hallucination
• palpitations

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Also, it is advisable to keep it in a cool and dry place below 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

Company packaging unit