Lavesta Tablet 10mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Typically, 10 mg is taken orally once daily, and depending on symptoms, the dosage may be increased to 20 mg once daily. Treatment for gastric ulcers lasts up to 8 weeks, while treatment for duodenal ulcers lasts up to 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks; if symptoms do not improve after 8 weeks, an additional 8 weeks of treatment with 10 mg or 20 mg may be administered. For relief of symptoms of gastroesophageal reflux disease: 10 mg is administered once daily. If symptoms are not controlled after 4 weeks, further evaluation is necessary. After symptoms resolve, on-demand therapy with 10 mg once daily may be used to manage any subsequent symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Dosage of 10 mg or 20 mg orally once daily may be used depending on the patient. For Helicobacter pylori eradication: Patients infected with Helicobacter pylori should be treated with eradication therapy. The recommended regimen is to administer this medication at 20 mg combined with clarithromycin 500 mg and amoxicillin 1 g twice daily for 7 days. For Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily, adjustable to a maximum of 120 mg based on individual patient needs. A dose of up to 100 mg can be administered once daily, while the 120 mg dose should be divided and administered as 60 mg twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to 1 year. For patients with liver impairment, adverse reactions of hepatic encephalopathy have been reported, thus it should be administered with caution. There is insufficient established safety for pediatric patients. Elderly patients should be administered with caution as liver function may often be impaired.

This medication should not be used by patients who are allergic to specific components or have a history of hypersensitivity reactions. Caution is particularly needed for patients with allergies to penicillins or macrolide antibiotics. Pregnant or breastfeeding women should not take this medication. Patients with impaired liver function or elderly patients should be especially cautious when using this medication, and caution is also required for those with a history of drug hypersensitivity. This medication can cause various side effects, and if hypersensitivity reactions such as skin rash or itching occur, use should be discontinued immediately. Regular check-ups are recommended as there may be effects on blood or liver function. Various adverse reactions in multiple bodily systems including the cardiovascular, gastrointestinal, neurological, respiratory, musculoskeletal, dermatological, ocular, and urinary tracts have been reported, necessitating caution. Long-term use of this medication may increase the risk of fractures due to osteoporosis and may cause electrolyte disturbances such as hypomagnesemia. Therefore, regular testing and management are necessary when taken long-term. This medication can interact with other drugs, so it is essential to consult a doctor or pharmacist when used in conjunction with antibiotics, antiviral drugs, anticoagulants, anticonvulsants, etc. There may be drowsiness or dizziness when driving or operating machinery, so caution is needed. In the event of overdose, there is no specific antidote, so it is important to receive symptomatic treatment. This medication should be swallowed whole and not chewed or crushed. It should be stored out of reach of children, and it is advisable not to transfer it to other containers. If any unusual symptoms or suspected side effects occur during treatment with this medication, immediate consultation with a healthcare professional is necessary.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, fulminant hepatitis, liver dysfunction, jaundice, syncope, pulmonary embolism, rectal bleeding, blood in stool, hepatic encephalopathy, seizures, confusion, dyspnea, apnea, respiratory depression, toxic epidermal necrolysis (Lyell's syndrome), mucocutaneous syndrome (Stevens-Johnson syndrome), angioedema, anaphylaxis, sudden death, coma, hemorrhagic diarrhea, severe allergic reactions, severe neurological symptoms, severe edema

Mild side effects

• Rash
• itching
• decrease in red blood cells
• decrease in white blood cells
• increase in white blood cells
• increase in eosinophils
• increase in neutrophils
• decrease in lymphocytes
• anemia
• petechiae

This medication should be stored in a tightly closed container to prevent air from entering, ideally at room temperature between 1 degree and 30 degrees Celsius. This will help maintain the effectiveness of the medication for a longer period.

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets per bottle, 300 tablets per bottle