Famciclovir Tablet (Famciclovir)

Adult dose

1. Treatment of herpes zoster Adults: Administer famciclovir orally at a dose of 250 mg 3 times daily for 7 days. It is preferable to start treatment as soon as symptoms appear after infection. 2. Treatment of first-episode genital herpes Adults: Administer this drug orally at a dose of 250 mg 3 times daily for 5 days. It is preferable to start treatment as soon as symptoms appear after infection. 3. Treatment of acute recurrent genital herpes Adults: Administer this drug orally at a dose of 125 mg 2 times daily for 5 days. It is preferable to start treatment during the prodromal period or as soon as symptoms appear after infection. 4. Suppression of recurrent genital herpes Adults: Administer this drug orally at a dose of 250 mg 2 times daily. Temporarily discontinue treatment periodically every 6～12 months to assess whether the natural course of the disease has changed. 5. Patients with renal impairment: Because creatinine clearance of this drug is reduced in patients with renal impairment, dose adjustment should be undertaken with caution. The dosage and administration for these patients are as follows. 1) Treatment of herpes zoster and first-episode genital herpes: Creatinine clearance (mL/min/1.73㎡) Dose 30～59 250 mg per dose, 2 times daily 10～29 250 mg per dose, once daily 2) Treatment of acute recurrent genital herpes: Creatinine clearance (mL/min/1.73㎡) Dose 30～59 125 mg per dose, 2 times daily 10～29 125 mg per dose, once daily 3) Suppression of recurrent genital herpes: Creatinine clearance (mL/min/1.73㎡) Dose 30～59 250 mg per dose, 2 times daily 10～29 125 mg per dose, 2 times daily 4) If only serum creatinine is known, creatinine clearance can be calculated using the following formula. Men: {weight (kg) × (140-age)}/ {72 × serum creatinine (mg/dL)} Women: 0.85 × the value calculated for men 5) Patients with renal impairment undergoing hemodialysis It is preferable to administer the drug every 48 hours, taking the interval between dialysis sessions into account. Because 4 hours of hemodialysis reduces the plasma concentration of this drug by approximately 75%, administer this drug immediately after dialysis. The recommended dose is 250mg for patients with herpes zoster and 125mg for patients with genital herpes. 6. Patients with hepatic impairment: No dose adjustment is necessary in patients with chronic compensated liver disease. There is insufficient treatment experience in patients with overt chronic decompensated liver disease; therefore, a clear recommended dose has not been established.

This medication should not be administered to specific patients. People who have had allergic reactions to this medication, its components, or its active ingredient, penciclovir, should not use it. Additionally, since it contains lactose, patients with lactose intolerance or certain genetic metabolic disorders should also avoid this medication. Patients with impaired kidney function should use this medication cautiously, and dosage adjustments may be necessary as needed. Various side effects may occur when taking this medication, such as headache, nausea, vomiting, dizziness, drowsiness, skin rash, abnormal liver function, and more. If symptoms are severe or persist, consultation with a physician is recommended. This medication does not cure genital herpes, and it may still be contagious even during treatment, so it is important to avoid sexual contact and maintain safe sexual practices. If dizziness, drowsiness, or confusion occurs during treatment, it is advisable to avoid driving or operating machinery. Elderly patients typically do not require dose adjustments, but in cases of decreased kidney function, dosage adjustments may be necessary. In case of overdose, immediate consultation with medical personnel is essential, and appropriate treatment, such as dialysis, may be required. This medication should be stored in a dry place below 30 degrees Celsius, out of reach of children, and it's best not to transfer it to another container.

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This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, storing it in a cool, dry place below 30 degrees Celsius is necessary to maintain its effectiveness.

Appearance

White round film-coated tablet

Package unit

21 tablets (21 tablets/PTP packaging x 1)